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在用于治疗疣的非处方产品中使用茶树油导致过敏性接触性皮炎扩散。

Spreading Allergic Contact Dermatitis to Tea Tree Oil in an Over-the-Counter Product Applied on a Wart.

机构信息

Section of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 70124 Bari, Italy.

Section of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari Aldo Moro, 70124 Bari, Italy.

出版信息

Medicina (Kaunas). 2022 Apr 19;58(5):561. doi: 10.3390/medicina58050561.

DOI:10.3390/medicina58050561
PMID:35629978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9146230/
Abstract

Tea tree oil is an essential oil obtained by distillation from the leaves and terminal branchlets of and is now present in numerous products for body care and self-medication. We report a case of allergic contact dermatitis to tea tree oil in a young man who was applying a lotion containing tea tree oil on a wart localized on the plantar aspect of the right big toe, which had previously been treated with cryotherapy. He developed a severe eczematous eruption on the right foot and the right leg, with subsequent id reactions affecting the right thigh, the contralateral lower limb, the trunk and the upper limbs. The lotion was discontinued, and the dermatitis resolved after topical corticosteroid therapy. Patch testing with the aforementioned lotion 10% pet. and oxidized tea tree oil 5% pet. identified tea tree oil as the culprit agent of the dermatitis. This case report confirms that products made of natural ingredients, often perceived to be harmless, can cause allergic reactions.

摘要

茶树油是一种从 和 的叶子和末端小枝中蒸馏得到的精油,现在存在于许多用于身体护理和自我治疗的产品中。我们报告了一例年轻男性因使用含有茶树油的乳液治疗右大脚趾跖侧的疣而引起的茶树油过敏性接触性皮炎。他的右脚和右腿出现严重的湿疹样皮疹,随后的 ID 反应影响到右大腿、对侧下肢、躯干和上肢。停止使用该乳液后,在局部使用皮质类固醇治疗后皮炎得到缓解。用上述乳液 10% pet. 和氧化茶树油 5% pet. 进行斑贴试验,发现茶树油是引起皮炎的罪魁祸首。本病例报告证实,由天然成分制成的产品,通常被认为是无害的,也可能引起过敏反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/f7983ea51a79/medicina-58-00561-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/6fde347054d8/medicina-58-00561-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/819d468f0c8f/medicina-58-00561-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/eafacdfb620c/medicina-58-00561-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/f7983ea51a79/medicina-58-00561-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/6fde347054d8/medicina-58-00561-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/819d468f0c8f/medicina-58-00561-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/eafacdfb620c/medicina-58-00561-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e424/9146230/f7983ea51a79/medicina-58-00561-g004.jpg

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Clin Dermatol. 2021 Jul-Aug;39(4):688-694. doi: 10.1016/j.clindermatol.2021.05.024. Epub 2021 May 19.
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Update on human papilloma virus - part I: epidemiology, pathogenesis, and clinical spectrum.人乳头瘤病毒最新进展 - 第一部分:流行病学、发病机制及临床谱
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Tea tree oil contact sensitization in children.儿童茶树油接触致敏
Contact Dermatitis. 2021 Feb;84(2):139-140. doi: 10.1111/cod.13699. Epub 2020 Sep 17.
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Italian Guidelines in Patch Testing - adapted from the European Society of Contact Dermatitis (ESCD).意大利斑贴试验指南 - 改编自欧洲接触性皮炎学会(ESCD)。
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