Kamsma T M, Boon W Q, Spitoni C, van Roij R
Institute for Theoretical Physics, Utrecht University, Princetonplein 5, 3584 CC Utrecht, The Netherlands.
Mathematical Institute, Utrecht University, Budapestlaan 6, 3584 CD Utrecht, The Netherlands.
Faraday Discuss. 2023 Oct 12;246(0):125-140. doi: 10.1039/d3fd00022b.
Conical channels filled with an aqueous electrolyte have been proposed as promising candidates for iontronic neuromorphic circuits. This is facilitated by a novel analytical model for the internal channel dynamics [T. M. Kamsma, W. Q. Boon, T. ter Rele, C. Spitoni and R. van Roij, , 2023, (26), 268401], the relative ease of fabrication of conical channels, and the wide range of achievable memory retention times by varying the channel lengths. In this work, we demonstrate that the analytical model for conical channels can be generalized to channels with an inhomogeneous surface charge distribution, which we predict to exhibit significantly stronger current rectification and more pronounced memristive properties in the case of bipolar channels, channels where the tip and base carry a surface charge of opposite sign. Additionally, we show that the use of bipolar conical channels in a previously proposed iontronic circuit features hallmarks of neuronal communication, such as all-or-none action potentials and spike train generation. Bipolar channels allow, however, for circuit parameters in the range of their biological analogues, and exhibit membrane potentials that match well with biological mammalian action potentials, further supporting their potential biocompatibility.
填充有水溶液电解质的锥形通道已被认为是离子电子神经形态电路的有前途的候选者。这得益于一种用于内部通道动力学的新型分析模型[T. M. Kamsma, W. Q. Boon, T. ter Rele, C. Spitoni和R. van Roij, , 2023, (26), 268401]、锥形通道相对容易制造，以及通过改变通道长度可实现的广泛的记忆保持时间范围。在这项工作中，我们证明了锥形通道的分析模型可以推广到具有不均匀表面电荷分布的通道，我们预测在双极通道（即尖端和基部带有相反符号表面电荷的通道）的情况下，这种通道将表现出明显更强的电流整流和更显著的忆阻特性。此外，我们表明在先前提出的离子电子电路中使用双极锥形通道具有神经元通信的特征，例如全或无动作电位和尖峰序列生成。然而，双极通道允许电路参数处于其生物类似物的范围内，并且表现出与生物哺乳动物动作电位良好匹配的膜电位，进一步支持了它们潜在的生物相容性。
