Kempner E S, Miller J H, McCreery M J
Anal Biochem. 1986 Jul;156(1):140-6. doi: 10.1016/0003-2697(86)90165-x.
The radiation sensitivity of glycoproteins is shown to depend only on the protein portion of the molecule. An artificially created glycoprotein containing glucose-6-phosphate dehydrogenase observes this rule as well as natural enzymes and receptors containing from 2 to 50% carbohydrate. No exceptions have been found. Radiation damage to carbohydrates occurs close to the site of the primary ionization, with little spread of damage into attached polypeptides.
糖蛋白的辐射敏感性仅取决于分子的蛋白质部分。人工合成的含葡萄糖 - 6 - 磷酸脱氢酶的糖蛋白遵循这一规律，天然酶和含2%至50%碳水化合物的受体也同样如此。尚未发现例外情况。碳水化合物的辐射损伤发生在初级电离部位附近，损伤很少扩散到相连的多肽中。
