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重度维生素B12缺乏所致精神病与癫痫发作:一例报告

Psychosis and Seizures Attributed to Severe Vitamin B12 Deficiency: A Case Report.

作者信息

Portillo Shellsea, Guevara Nehemias A, Francis-Morel Garry

机构信息

Internal Medicine, St. Barnabas Hospital Health System, Bronx, USA.

Internal Medicine, St. Barnabas Medical Center, Bronx, USA.

出版信息

Cureus. 2023 Jun 2;15(6):e39889. doi: 10.7759/cureus.39889. eCollection 2023 Jun.

Abstract

Vitamin B12 deficiency is known to cause a variety of symptoms, including megaloblastic anemia, glossitis, and neuropsychiatric disorders. This case report describes a patient who presented with cognitive decline, psychosis, and seizures due to a severe vitamin B12 deficiency. Following treatment with vitamin supplementation therapy, the patient's condition significantly improved. The literature has also documented similar neuropsychiatric manifestations of vitamin B12 deficiency, highlighting the potential for symptom reversal with prompt and appropriate treatment. Therefore, early diagnosis and treatment of vitamin B12 deficiency are critical to preventing potentially irreversible neurological damage.

摘要

众所周知,维生素B12缺乏会导致多种症状,包括巨幼细胞贫血、舌炎和神经精神障碍。本病例报告描述了一名因严重维生素B12缺乏而出现认知能力下降、精神病和癫痫发作的患者。在接受维生素补充治疗后,患者的病情明显改善。文献中也记录了维生素B12缺乏的类似神经精神表现,强调了及时和适当治疗后症状逆转的可能性。因此,早期诊断和治疗维生素B12缺乏对于预防潜在的不可逆神经损伤至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/149b/10315186/78fe8ba65747/cureus-0015-00000039889-i01.jpg

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