Ahmed Iftekhar, Salsabil Lubaba, Hossain Md Jamal, Shahriar Mohammad, Bhuiyan Mohiuddin Ahmed, Islam Md Rabiul
Department of Pharmacy University of Asia Pacific Dhaka Bangladesh.
Department of Pharmacy State University of Bangladesh Dhaka Bangladesh.
Health Sci Rep. 2023 Jul 3;6(7):e1395. doi: 10.1002/hsr2.1395. eCollection 2023 Jul.
Marburg virus disease (MVD) caused by the Marburg virus has a high mortality rate. fruit bats act as the natural reservoir host of the virus. But it can also potentially be transmitted from person to person through direct contact with body secretions. The recent outbreaks have already killed seven people out of nine confirmed cases in Equatorial Guinea and five patients out of eight confirmed cases in Tanzania. In the recent past, Ghana reported three MVD cases and two associated deaths in 2022. Specific treatments or vaccines are unavailable for MVD, and supportive care is the primary treatment option. The history of MVD outbreaks and the current scenario show its potential to become an emerging threat to global public health. The recent outbreaks in Tanzania and Equatorial Guinea have already caused a high fatality rate. The absence of effective treatment and vaccines raises concerns about the potential to cause widespread harm. Besides, its capacity for human-to-human transmission and potential to cross the country's border could result in a multicountry outbreak. Therefore, we recommend intensive surveillance of MVD, preventative measures, and early detection to limit the spread of the disease and prevent another pandemic.
由马尔堡病毒引起的马尔堡病毒病(MVD)死亡率很高。果蝠是该病毒的天然宿主。但它也可能通过直接接触身体分泌物在人与人之间传播。最近的疫情已导致赤道几内亚9例确诊病例中的7人死亡,坦桑尼亚8例确诊病例中的5人死亡。近期,加纳在2022年报告了3例马尔堡病毒病病例和2例相关死亡病例。马尔堡病毒病没有特效治疗方法或疫苗,支持性护理是主要的治疗选择。马尔堡病毒病的疫情历史和当前情况表明,它有可能成为全球公共卫生的新威胁。坦桑尼亚和赤道几内亚最近的疫情已导致高死亡率。缺乏有效的治疗方法和疫苗引发了对其可能造成广泛危害的担忧。此外,它的人际传播能力和跨越国界的可能性可能导致多国疫情爆发。因此,我们建议对马尔堡病毒病进行强化监测、采取预防措施并尽早发现,以限制疾病传播并防止再次爆发大流行。