Chowdhury Partha Pratim Deb, Haque Md Anamul, Ahamed Bulbul, Tanbir Md, Islam Md Rabiul
Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh.
Clin Pathol. 2022 Oct 21;15:2632010X221131660. doi: 10.1177/2632010X221131660. eCollection 2022 Jan-Dec.
Monkeypox is a zoonotic disease caused by the monkeypox virus (MPXV). It was an epidemic infection among African countries over the last few decades. In 2022, MPXV has been broke through in Africa, America, Eastern Mediterranean, Europe, South-East Asia, and Western Pacific region. This widespread infection of MPXV has created panic across the nations, and the WHO has declared a global public health emergency due to the multi-country MPX outbreak. We prepared this brief report on the MPX outbreak 2022 by extracting data from Scopus, PubMed, and website databases. We manually read all the relevant articles from our target databases. The rapid spread of MPX infection in around a 100 countries has threatened the global healthcare systems. The available epidemiological data revealed that sexual orientations and encounters are potential contributing factors for monkeypox infections. However, it has not been categorized as a sexually transmitted infection. Also, MPXV can transfer from 1 individual to others in many ways. The empowerment of this old foe has created additional pressure and threat on the healthcare authorities during the ongoing Covid-19 pandemic. Effective preventive measures, social awareness, and therapeutic approaches can reduce this extra burden on the healthcare system across the countries. Focusing only on sexual orientations and encounters as risk factors for MPX infection might increase stigma that will be another barrier to controlling and preventing MPXV spread. Therefore, we should be careful in delivering messages about MPX infection to the general population. Also, we recommend repositioning the existing smallpox vaccines and antivirals in MPX infection until the development of specific antiviral agents against this infection.
猴痘是一种由猴痘病毒（MPXV）引起的人畜共患病。在过去几十年里，它在非洲国家中是一种流行性感染疾病。2022年，猴痘病毒在非洲、美洲、东地中海、欧洲、东南亚和西太平洋地区出现了传播。这种猴痘病毒的广泛传播在各国引发了恐慌，由于多国出现猴痘疫情，世界卫生组织已宣布全球突发公共卫生事件。我们通过从Scopus、PubMed和网站数据库中提取数据，编写了这份关于2022年猴痘疫情的简要报告。我们手动阅读了目标数据库中所有相关文章。猴痘感染在约100个国家的迅速传播威胁到了全球医疗系统。现有的流行病学数据显示，性取向和性接触是猴痘感染的潜在促成因素。然而，它尚未被归类为性传播感染。此外，猴痘病毒可以通过多种方式从一个人传播给其他人。在当前的新冠疫情期间，这个老对手的肆虐给卫生当局带来了额外的压力和威胁。有效的预防措施、社会意识和治疗方法可以减轻各国医疗系统的这一额外负担。仅将性取向和性接触作为猴痘感染的风险因素可能会增加污名化，这将成为控制和预防猴痘病毒传播的另一个障碍。因此，我们在向普通民众传达有关猴痘感染的信息时应谨慎。此外，我们建议在研发针对这种感染的特异性抗病毒药物之前，重新调整现有的天花疫苗和抗病毒药物用于猴痘感染的治疗。
