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在微观层面测量体内红细胞血流速度的方法。

Methods to measure blood flow velocity of red blood cells in vivo at the microscopic level.

作者信息

Slaaf D W, Jeurens T J, Tangelder G J, Reneman R S, Arts T

出版信息

Ann Biomed Eng. 1986;14(2):175-86. doi: 10.1007/BF02584268.

DOI:10.1007/BF02584268
PMID:3740569
Abstract

Several methods to measure red blood cell velocity in microvessels by electronic means are discussed. Signals are generated by the red blood cells present in the microscopic image of the microvessels. These signals can be converted to obtain an output signal proportional to the actual red blood cell velocity. The method of spatial filtering by interlacing gratings is discussed in terms of a filter with an input signal. Adaptation of optical factors that might improve the velocity measurement is obtained by a mathematical analysis. Different methods of correlation are presented. The temporal correlation (dual slit and video window) and spatial correlation methods are discussed in relation to factors influencing the quality of the correlogram, the peak of which is proportional to red blood cell velocity. The conversion of red blood cell velocity to volume flow is put in perspective.

摘要

讨论了几种通过电子手段测量微血管中红细胞速度的方法。信号由微血管显微图像中存在的红细胞产生。这些信号可以被转换以获得与实际红细胞速度成比例的输出信号。从具有输入信号的滤波器角度讨论了通过交错光栅进行空间滤波的方法。通过数学分析获得了可能改善速度测量的光学因素的适配。介绍了不同的相关方法。讨论了时间相关(双缝和视频窗口)和空间相关方法与影响相关图质量的因素的关系,相关图的峰值与红细胞速度成比例。阐述了红细胞速度到体积流量的转换。

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Methods to measure blood flow velocity of red blood cells in vivo at the microscopic level.在微观层面测量体内红细胞血流速度的方法。
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本文引用的文献

1
A method for on-line measurements of red cell velocity in microvessels using computerized frame-by-frame analysis of television images.一种利用电视图像的计算机逐帧分析在线测量微血管中红细胞速度的方法。
Microvasc Res. 1980 Jul;20(1):1-8. doi: 10.1016/0026-2862(80)90014-x.
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A bidirectional optical (BDO) three-stage prism grating system for on-line measurement of red blood cells velocity in microvessels.
Microvasc Res. 1981 Jul;22(1):110-22. doi: 10.1016/0026-2862(81)90115-1.
3
Experimental calibration of a two-stage prism-grating system for measuring cell velocity.用于测量细胞速度的两级棱镜-光栅系统的实验校准。
血液-组织交换动力学的分形分析
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An optical doppler intravital velocimeter.一种光学多普勒活体测速仪。
Microvasc Res. 1984 Jan;27(1):117-27. doi: 10.1016/0026-2862(84)90047-5.
5
Analysis of the bidirectional optical three-stage prism grating system for red blood cell velocity measurements in microvessels.用于微血管中红细胞速度测量的双向光学三阶段棱镜光栅系统分析。
Med Biol Eng Comput. 1984 Nov;22(6):521-8. doi: 10.1007/BF02443865.
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Erythrocyte velocity measurement in microvessels by a two-slit photometric method.采用双缝光度法测量微血管中的红细胞速度。
J Appl Physiol. 1967 Feb;22(2):333-7. doi: 10.1152/jappl.1967.22.2.333.
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A television method for measuring capillary red cell velocities.一种测量毛细血管红细胞速度的电视方法。
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Capillary red blood cell velocity measurements in human nailfold by videodensitometric method.
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Capillary flow velocity measurements in vivo and in situ by television methods.
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RBC velocity profiles in arterioles and venules of the rabbit omentum.兔网膜小动脉和小静脉中的红细胞速度剖面。
Microvasc Res. 1975 Sep;10(2):153-64. doi: 10.1016/0026-2862(75)90003-5.