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透气、可纺织嵌入的微流控汗液传感器。

Perspiration permeable, textile embeddable microfluidic sweat sensor.

机构信息

School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui, 230026, PR China; i-Lab, Key Laboratory of Multifunctional Nanomaterials and Smart Systems, Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (CAS), 398 Ruoshui Road, Suzhou, Jiangsu, 215123, PR China.

School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui, 230026, PR China; i-Lab, Key Laboratory of Multifunctional Nanomaterials and Smart Systems, Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (CAS), 398 Ruoshui Road, Suzhou, Jiangsu, 215123, PR China.

出版信息

Biosens Bioelectron. 2023 Oct 1;237:115504. doi: 10.1016/j.bios.2023.115504. Epub 2023 Jun 29.

Abstract

Epidermal microfluidic devices are continuously being developed for efficient sweat collection and sweat rate detection. However, most microfluidic designs ignore the use of airtight/adhesive substrate will block the natural perspiration of the covered sweat pores, which will seriously affect normal sweat production and long-term wearable comfort. Herein, we present a Janus textile-embedded microfluidic sensor platform with high breathability and directional sweat permeability for synchronous sweat rate and total electrolyte concentration detection. The device consists of a hollowed-out serpentine microchannel with interdigital electrodes and Janus textile. The dual-mode signal of the sweat rate (0.2-4.0 μL min) and total ionic charge concentration (10-200 mmol L) can be obtained synchronously by decoupling conductance step signals generated when sweat flows through alternating interdigitated spokes at equal intervals in the microchannel. Meanwhile, the hollowed-out microchannel structure significantly reduces the coverage area of the sensor on the skin, and the Janus textile-embedded device ensures a comfortable skin/device interface (fewer sweat pores are blocked) and improves breathability (503.15 g m d) and sweat permeability (directional liquid transportation) during long-term monitoring. This device is washable and reusable, which shows the potential to integrate with clothing and smart textile, and thus facilitate the practicality of wearable sweat sensors for personalized healthcare.

摘要

表皮微流控装置不断被开发出来,以实现高效的汗液收集和汗液速率检测。然而,大多数微流控设计忽略了使用密封/粘性基底会阻碍被覆盖的汗孔的自然出汗,这将严重影响正常的汗液产生和长期佩戴舒适性。在此,我们提出了一种具有高透气性和定向汗液渗透性的 Janus 纺织嵌入式微流控传感器平台,用于同步汗液速率和总电解质浓度检测。该装置由带有叉指电极的中空蛇形微通道和 Janus 纺织品组成。通过解耦在微通道中以相等间隔流过交替叉指辐条时产生的电导阶跃信号,可以同时获得汗液速率(0.2-4.0 μL min)和总离子电荷浓度(10-200 mmol L)的双模式信号。同时,中空微通道结构显著减小了传感器在皮肤上的覆盖面积,而嵌入 Janus 纺织品的装置确保了舒适的皮肤/设备界面(较少的汗孔被堵塞),并提高了透气性(503.15 g m d)和汗液渗透性(定向液体输送),从而实现长期监测。该装置可清洗且可重复使用,这显示了与服装和智能纺织品集成的潜力,从而有利于个性化医疗用可穿戴汗液传感器的实用性。

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