Department of Orthopedic Surgery, Tohoku University School of Medicine.
Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University Graduate School of Public Health.
Tohoku J Exp Med. 2023 Sep 13;261(1):43-49. doi: 10.1620/tjem.2023.J053. Epub 2023 Jul 6.
Low back pain (LBP) and neck pain (NP) are common health problems worldwide. LBP often coexists with NP; however, the association between these pains remains unclear. The purpose of this study was to clarify the association between LBP and NP, focusing on dose-dependent effects. This study used a 3-year longitudinal cohort data of people living in disaster-stricken areas after the Great East Japan Earthquake (n = 2,118). LBP and NP were assessed at 4, 5, 6, and 7 years after the disaster. LBP was categorized according to its frequency. Multivariate logistic regression analyses were performed to assess the association between LBP and NP, and the effect of preceding LBP on the subsequent onset of NP, according to the frequency of LBP. LBP was significantly associated with NP, and the association was stronger with increased frequency of LBP. Adjusted odds ratios (95% confidence intervals) were 2.40 (1.71-3.37) for "1", 3.99 (2.82-5.66) for "2", and 6.08 (4.40-8.41) for "≥ 3" in frequency when the absence of LBP was used as a reference (p for trend < 0.001). Furthermore, preceding LBP was significantly associated with subsequent onset of NP, and the effect was stronger with increased frequency of LBP. Adjusted odds ratios (95% confidence intervals) were 2.44 (1.62-3.68) for "1" and 2.68 (1.77-4.05) for "≥ 2" in frequency when the absence of LBP was used as a reference (p for trend < 0.001). LBP is associated with NP in a dose-dependent manner. The association between LBP and NP should be considered to effectively treat these pains.
下背痛（LBP）和颈痛（NP）是全球常见的健康问题。LBP 常与 NP 共存；然而，这些疼痛之间的关联尚不清楚。本研究旨在阐明 LBP 和 NP 之间的关联，重点关注剂量依赖性效应。本研究使用了大东部日本地震后生活在灾区的人群的 3 年纵向队列数据（n=2118）。在灾难发生后 4、5、6 和 7 年评估了 LBP 和 NP。根据其频率对 LBP 进行分类。进行多变量逻辑回归分析，以评估 LBP 和 NP 之间的关联，以及先前的 LBP 对随后发生 NP 的影响，根据 LBP 的频率。LBP 与 NP 显著相关，且随着 LBP 频率的增加，相关性更强。调整后的优势比（95%置信区间）分别为频率为“1”时的 2.40（1.71-3.37）、“2”时的 3.99（2.82-5.66）和“≥3”时的 6.08（4.40-8.41），当以无 LBP 为参考时（p<0.001）。此外，先前的 LBP 与随后发生的 NP 显著相关，且随着 LBP 频率的增加，其影响更强。当以无 LBP 为参考时，调整后的优势比（95%置信区间）分别为频率为“1”时的 2.44（1.62-3.68）和“≥2”时的 2.68（1.77-4.05）（p<0.001）。LBP 与 NP 呈剂量依赖性相关。应考虑 LBP 和 NP 之间的关联，以有效治疗这些疼痛。
