Zhonghua Yan Ke Za Zhi. 2023 Jul 11;59(7):518-525. doi: 10.3760/cma.j.cn112142-20230313-00098.
Vogt-Koyanagi-Harada (VKH) syndrome is an autoimmune disorder characterized by bilateral granulomatous uveitis, and it is one of the common uveitis entities causing blindness in China. The clinical manifestations of VKH disease vary significantly at different stages. Most patients can achieve a complete control of the uveitis and good visual prognosis if appropriate treatment is initiated. Therefore, an extensive investigation and literature review on this disease have been performed by the experts in the Uveitis and Ocular Immunology Group of Chinese Ophthalmologist Association and the Ocular Immunology Group of Ophthalmology Society of Chinese Medical Association. Consensus opinions on VKH syndrome have been developed in an attempt to provide general guidance and reference in the diagnosis and treatment of this disease.
伏格特-小柳-原田(VKH)综合征是一种自身免疫性疾病,其特征为双侧肉芽肿性葡萄膜炎,是中国导致失明的常见葡萄膜炎类型之一。VKH病在不同阶段的临床表现差异很大。如果开始适当治疗,大多数患者的葡萄膜炎可以得到完全控制,视觉预后良好。因此,中华医学会眼科学分会葡萄膜炎与眼免疫学组以及中华医学会眼科分会眼免疫学组的专家对该疾病进行了广泛的调查和文献综述。已就VKH综合征形成了共识意见,旨在为该疾病的诊断和治疗提供一般指导和参考。