Dover J S, Phillips T J, Burns D A, Krafchik B R
Arch Dermatol. 1986 Aug;122(8):887-9.
The coexistence of disseminated superficial actinic porokeratosis (DSAP) with other variants of porokeratosis is rare. We report three such cases: DSAP with porokeratosis of Mibelli; DSAP with linear porokeratosis; and DSAP occurring in the mother of a girl with linear porokeratosis. Although different areas of skin and different family members usually express the same morphological variant, we suggest that the simultaneous expression of two closely linked gene loci could explain the coexistence of different porokeratotic variants.
播散性浅表性光化性汗孔角化症(DSAP)与其他汗孔角化症变体并存的情况较为罕见。我们报告了三例此类病例:DSAP合并米贝利汗孔角化症;DSAP合并线状汗孔角化症;以及线状汗孔角化症女童的母亲患有DSAP。尽管皮肤的不同部位和不同家庭成员通常表现出相同的形态学变体,但我们认为两个紧密连锁的基因位点同时表达可以解释不同汗孔角化症变体的并存现象。