类风湿关节炎患者中淀粉样变性病和肾脏疾病导致的死亡率。
Mortality from amyloidosis and renal diseases in patients with rheumatoid arthritis.
作者信息
Laakso M, Mutru O, Isomäki H, Koota K
出版信息
Ann Rheum Dis. 1986 Aug;45(8):663-7. doi: 10.1136/ard.45.8.663.
Abstract
Patients with rheumatoid arthritis (RA), 500 men and 500 women, aged 40 years and over, together with a control population matched by age and sex, were observed over a 10 year period. The overall mortality was significantly higher in both men and women with rheumatoid arthritis than in the controls due to an excess mortality from infections and cardiovascular and renal diseases. During the follow up 31 patients with RA (12 male, 19 female) and one male control subject died from amyloidosis and 42 RA patients (19 male, 23 female) and one male control from renal diseases. The most important causes of renal deaths were chronic nephritis and renal infections.
摘要
对500名年龄在40岁及以上的类风湿性关节炎（RA）男性患者和500名同年龄段的女性患者，以及按年龄和性别匹配的对照人群进行了为期10年的观察。类风湿性关节炎患者中男性和女性的总体死亡率均显著高于对照组，原因是感染、心血管疾病和肾脏疾病导致的死亡人数过多。在随访期间，31名RA患者（12名男性，19名女性）和1名男性对照受试者死于淀粉样变性，42名RA患者（19名男性，23名女性）和1名男性对照死于肾脏疾病。肾脏死亡的最重要原因是慢性肾炎和肾脏感染。
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