类风湿关节炎患者的十年死亡率及死亡原因
Ten year mortality and causes of death in patients with rheumatoid arthritis.
作者信息
Mutru O, Laakso M, Isomäki H, Koota K
出版信息
Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1797-9. doi: 10.1136/bmj.290.6484.1797.
Abstract
Five hundred men and 500 women, aged 40 or over, with rheumatoid arthritis, together with a control population matched for age and sex, were observed over 10 years. During that time 352 patients with rheumatoid arthritis (208 men, 144 women) and 221 controls (148 men, 73 women) died. The overall mortality was significantly higher (p less than 0.0001) in both men and women with rheumatoid arthritis than in the controls. Infections and cardiovascular and renal diseases (especially amyloidosis) appeared to be the main causes of death in rheumatoid arthritis.
摘要
对500名年龄在40岁及以上的类风湿关节炎男性患者和500名年龄在40岁及以上的类风湿关节炎女性患者，以及一组年龄和性别匹配的对照人群进行了为期10年的观察。在此期间，352例类风湿关节炎患者（208名男性，144名女性）和221名对照者（148名男性，73名女性）死亡。类风湿关节炎男性和女性患者的总死亡率均显著高于对照组（p<0.0001）。感染、心血管疾病和肾脏疾病（尤其是淀粉样变性）似乎是类风湿关节炎患者的主要死因。
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