使用度普利尤单抗治疗的有色人种皮肤中的红皮病型大疱性类天疱疮。

Erythrodermic Bullous Pemphigoid in Skin of Color Treated With Dupilumab.

作者信息

Sanfilippo Eric, Gonzalez Lopez Adrianna, Saardi Karl M

出版信息

J Drugs Dermatol. 2023 Jul 1;22(7):685-686. doi: 10.36849/JDD.7196.

Abstract

Bullous pemphigoid (BP) is an autoimmune blistering disease that typically presents with pruritic, tense bullae in elderly patients.1 Several recognized presentations deviate from the classic bullous eruption, and erythrodermic BP, in particular, is thought to be a rare phenomenon. Herein, we present a case of erythrodermic BP in an African American male who initially presented with erythroderma in the absence of tense bullae. There have been no reports on erythrodermic BP in skin of color to our knowledge. The patient rapidly improved after treatment was started with dupilumab. He developed classic tense bullae seen in BP once dupilumab was discontinued.Sanfilippo E, Gonzalez Lopez A, Saardi KM. Erythrodermic bullous pemphigoid in skin of color treated with dupilumab. J Drugs Dermatol. 2023;22(7):685-686. doi:10.36849/JDD.7196. &nbsp.

摘要

大疱性类天疱疮（BP）是一种自身免疫性水疱病，通常在老年患者中表现为瘙痒性、紧张性大疱。有几种公认的表现形式与典型的水疱性皮疹不同，特别是红皮病型BP被认为是一种罕见现象。在此，我们报告一例非裔美国男性红皮病型BP病例，该患者最初表现为红皮病，无紧张性大疱。据我们所知，尚无关于有色人种皮肤红皮病型BP的报道。患者开始使用度普利尤单抗治疗后迅速好转。停用度普利尤单抗后，他出现了BP中常见的典型紧张性大疱。Sanfilippo E, Gonzalez Lopez A, Saardi KM. 用度普利尤单抗治疗的有色人种皮肤红皮病型大疱性类天疱疮。《药物皮肤病学杂志》。2023;22(7):685-686。doi:10.36849/JDD.7196。