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垂直性凝视麻痹与内侧纵束的嘴侧间质核

Vertical glaze paralysis and the rostral interstitial nucleus of the medial longitudinal fasciculus.

作者信息

Büttner-Ennever J A, Büttner U, Cohen B, Baumgartner G

出版信息

Brain. 1982 Mar;105(Pt 1):125-49. doi: 10.1093/brain/105.1.125.

DOI:10.1093/brain/105.1.125
PMID:7066670
Abstract

The rostral interstitial nucleus of the medial longitudinal fasciculus in known to participate in the generation of fast vertical eye movements in the monkey. A cell group homologous to this nucleus has been identified in the human brain. In man the nucleus lies dorsomedial to the anterior pole of the red nucleus, rostral to the interstitial nucleus of Cajal, and lateral to the nucleus of Darkschewitsch. Reconstructions of lesions in patients with different types of vertical gaze paralysis show that destruction of the rostral interstitial nucleus of the MLF bilaterally leads to an impairment of fast vertical eye movements. We propose that the nucleus participates in the production of vertical saccades and quick phases of nystagmus in man. Preservation of its integrity is not necessary for the production of vestibular compensatory eye movements in the vertical plane.

摘要

已知内侧纵束的嘴侧间质核参与猴子快速垂直眼球运动的产生。在人类大脑中已鉴定出与该核同源的细胞群。在人类中,该核位于红核前极的背内侧、 Cajal间质核的嘴侧以及Darkschewitsch核的外侧。对不同类型垂直凝视麻痹患者病变的重建显示,双侧内侧纵束嘴侧间质核的破坏会导致快速垂直眼球运动受损。我们认为该核参与人类垂直扫视和眼球震颤快相的产生。其完整性的保留对于垂直平面前庭代偿性眼球运动的产生并非必需。

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