Schaeffer K W, Parsons O A
Alcohol. 1986 May-Jun;3(3):175-9. doi: 10.1016/0741-8329(86)90041-8.
The relationships between alcohol intake (per occasion over time) and performance on neuropsychological tests, as they might be affected by anxiety and depression, were investigated in both an alcoholic (N = 60) and social drinking (N = 43) sample. alcoholics, a Maximum Quantity Frequency (MQF) of alcohol consumed over the previous six months was found to be the best predictor of an impairment index. Neither anxiety nor depression were correlated with test performance. In social drinkers, anxiety was the best predictor of performance on the impairment index; depression was not predictive. Neither MQF nor a commonly used measure of drinking behaviors, weighted quantity per occasion (QPO), significantly predicted performance in the social drinkers once anxiety was accounted for. The results support the assumption that in alcoholics the greater and more frequent the alcohol ingestion, the more the brain's functioning is disrupted, at least as reflected in neuropsychological test performance. Anxiety appears to play a major role in the test performance of social drinkers and should be monitored in future studies in this research area.
在一个酗酒者样本（N = 60）和社交饮酒者样本（N = 43）中，研究了饮酒量（每次饮酒量随时间变化）与神经心理学测试表现之间的关系，这些关系可能会受到焦虑和抑郁的影响。在酗酒者中，发现过去六个月内饮酒的最大量频率（MQF）是损伤指数的最佳预测指标。焦虑和抑郁与测试表现均无相关性。在社交饮酒者中，焦虑是损伤指数表现的最佳预测指标；抑郁则无预测作用。一旦考虑到焦虑因素，MQF和常用的饮酒行为测量指标——每次饮酒加权量（QPO），均不能显著预测社交饮酒者的表现。结果支持这样的假设，即对于酗酒者而言，饮酒量越大且越频繁，大脑功能受干扰就越严重，至少在神经心理学测试表现中有所体现。焦虑似乎在社交饮酒者的测试表现中起主要作用，在该研究领域的未来研究中应予以监测。
