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味觉和嗅觉功能障碍患者腮腺唾液钙调蛋白水平低。

Low parotid saliva calmodulin in patients with taste and smell dysfunction.

作者信息

Law J S, Henkin R I

出版信息

Biochem Med Metab Biol. 1986 Aug;36(1):118-24. doi: 10.1016/0885-4505(86)90115-5.

DOI:10.1016/0885-4505(86)90115-5
PMID:3741698
Abstract

Parotid saliva calmodulin was found both in 32 normal volunteers and in 60 patients with taste and smell dysfunction; salivary calmodulin concentration was significantly lower in the patients than in the volunteers. There were no differences in salivary calmodulin concentration with respect to age, sex, or salivary flow rate in either normal volunteers or patients. When patients were categorized by diagnosis, calmodulin concentration was found to be decreased in all patient groups. The concentration of calmodulin in saliva was about 10 times that found in serum, suggesting that the parotid gland is a major source of this protein.

摘要

在32名正常志愿者以及60名味觉和嗅觉功能障碍患者的腮腺唾液中均发现了钙调蛋白;患者唾液中的钙调蛋白浓度显著低于志愿者。无论是正常志愿者还是患者,唾液钙调蛋白浓度在年龄、性别或唾液流速方面均无差异。当根据诊断对患者进行分类时,发现所有患者组的钙调蛋白浓度均降低。唾液中钙调蛋白的浓度约为血清中的10倍,这表明腮腺是这种蛋白质的主要来源。

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