Sato Y, Mizoguchi K, Sato Y, Utsunomiya H, Hayashi T, Kaji M
No To Shinkei. 1986 May;38(5):469-73.
A very rare case of peptostreptococcal meningitis associated with subarachnoid hemorrhage and subdural hematoma was reported. A 25-year-old man was admitted to St. Mary's Hospital on November 6, 1984 with a few day's history of headache and low grade fever. On admission, he had high grade fever (39.2 degrees C) and tachycardia (110/min). There were no neurological deficits other than neck stiffness and Kernig's sign. The cerebrospinal fluid (CSF) which was obtained through lumbar puncture showed watery clear appearance, white cell count of 32/3 mm3 (mononuclear: polymorphonuclear = 4:5), protein 76 mg/dl and glucose 8 mg/dl. It was found to be sterile. However, peptostreptococcus was found in his peripheral blood culture. He was diagnosed peptostreptococcal meningitis. After administration of antibiotics, laboratory test result of CSF improved gradually so as his meningeal irritation signs. After 25 days of hospitalization, he developed suddenly severe headache. CSF showed bloody and xanthochromic appearance, and CT scan revealed a subdural hematoma in the left fronto-temporal convexity. Although we suspected formation of mycotic aneurysm caused by the meningitis and its rupture, cerebral angiography revealed no abnormality except for the findings of subdural hematoma. The subdural hematoma was completely absorbed and he was discharged 79 days after admission without having any neurological deficit. We concluded that such a mycotic aneurysm was too small to be detected by the cerebral angiography.
报道了一例非常罕见的消化链球菌脑膜炎合并蛛网膜下腔出血和硬膜下血肿的病例。一名25岁男性于1984年11月6日因头痛和低热数日入住圣玛丽医院。入院时,他高热(39.2摄氏度)且心动过速(110次/分钟)。除颈部僵硬和凯尔尼格征外,无其他神经功能缺损。通过腰椎穿刺获取的脑脊液外观呈水样清澈,白细胞计数为32/3立方毫米(单核细胞:多形核细胞=4:5),蛋白质76毫克/分升,葡萄糖8毫克/分升。脑脊液培养无菌。然而,在他的外周血培养中发现了消化链球菌。他被诊断为消化链球菌脑膜炎。使用抗生素后,脑脊液的实验室检查结果逐渐改善,脑膜刺激征也随之改善。住院25天后,他突然出现剧烈头痛。脑脊液呈血性且有黄变,CT扫描显示左额颞叶凸面有硬膜下血肿。尽管我们怀疑是脑膜炎导致的霉菌性动脉瘤形成并破裂,但脑血管造影除硬膜下血肿的表现外未发现异常。硬膜下血肿完全吸收,他入院79天后出院,无任何神经功能缺损。我们得出结论,这样的霉菌性动脉瘤太小,无法通过脑血管造影检测到。