Wennergren M, Krantz M, Hjalmarson O, Karlsson K
Br J Obstet Gynaecol. 1986 Aug;93(8):799-803.
The influence of the time interval from rupture of the membranes to delivery on neonatal respiratory adaptation was analysed in a prospective study of all infants born in Göteborg, Sweden in one year. The correlation between the incidence of respiratory disorders and the rupture-delivery interval was analysed in all preterm infants (less than or equal to 36 weeks, n = 240) and in all term infants born by caesarean section (n = 452). A uniform pattern was found for all preterm infants, irrespective of mode of delivery, and for the term infants born by caesarean section. The curve was 'U-shaped' with higher incidence of respiratory diseases in infants born immediately after rupture of the membranes than in those born 3-36 h after membrane rupture. The incidence increased again in infants born greater than 36 h after membrane rupture. The same pattern was found for all kinds of respiratory diseases including idiopathic respiratory distress syndrome. Therefore, there seems to be no advantage in postponing delivery greater than 36 h after rupture of the membranes.
在一项对瑞典哥德堡一年内出生的所有婴儿的前瞻性研究中，分析了从胎膜破裂到分娩的时间间隔对新生儿呼吸适应的影响。对所有早产儿（小于或等于36周，n = 240）和所有剖宫产的足月儿（n = 452），分析了呼吸障碍发生率与胎膜破裂至分娩间隔之间的相关性。发现所有早产儿（无论分娩方式如何）以及剖宫产的足月儿呈现出一致的模式。曲线呈“U”形，胎膜破裂后立即出生的婴儿呼吸系统疾病发生率高于胎膜破裂后3 - 36小时出生的婴儿。胎膜破裂后超过36小时出生的婴儿发病率再次上升。包括特发性呼吸窘迫综合征在内的各类呼吸系统疾病均呈现相同模式。因此，在胎膜破裂后超过36小时推迟分娩似乎并无益处。
