Christiansen K, Carlsen J
Biochim Biophys Acta. 1986 Sep 11;860(3):503-9. doi: 10.1016/0005-2736(86)90547-x.
Cytochrome b5 is incorporated into vesicles of the endoplasmic reticulum as protein-lysophosphatidylcholine micelles. Cytochrome b5 becomes firmly bound to the membrane and at the same time lysophosphatidylcholine is acylated by acyltransferases of the endoplasmic reticulum and converted into the membrane component phosphatidylcholine. The possibility of an insertion of cytochrome b5 into the endoplasmic reticulum in vivo by this mechanism is discussed.
细胞色素b5以内质网的蛋白质-溶血磷脂酰胆碱微团形式整合到内质网的囊泡中。细胞色素b5与膜紧密结合，同时溶血磷脂酰胆碱被内质网的酰基转移酶酰化并转化为膜成分磷脂酰胆碱。本文讨论了通过这种机制细胞色素b5在体内插入内质网的可能性。
