Fentiman I S, Millis R R, Chaudary M A, King R J, Miller K J, Hayward J L
Br J Surg. 1986 Aug;73(8):610-2. doi: 10.1002/bjs.1800730807.
A comparison has been made of the survival of contemporary patients treated by mastectomy in whom the original diagnosis was made by either Tru-cut biopsy or by excision biopsy. After a minimum of 5 years of follow-up there was no difference in survival between those biopsied by either method. When subdivided by tumour size again no differences emerged. Among those patients in whom the original Tru-cut biopsy was false negative there was no difference in survival compared with those treated by excision biopsy. This suggests that Tru-cut biopsy is a safe method for obtaining a histological diagnosis in operable breast cancer. Furthermore, when the receptor status of the tumours from the two groups was determined, there was no difference in the percentage of oestrogen receptor positive tumours, nor in the mean receptor value. However, there were more progesterone receptor positive tumours among the Tru-cut group, suggesting that a better tumour sample could have been submitted for analysis. This may be yet another advantage for the use of Tru-cut biopsy for the diagnosis of breast cancer.
对当代接受乳房切除术的患者进行了比较，这些患者最初的诊断是通过粗针活检或切除活检做出的。经过至少5年的随访，两种活检方法的患者生存率没有差异。按肿瘤大小细分后，也没有出现差异。在那些最初粗针活检为假阴性的患者中，与接受切除活检的患者相比，生存率没有差异。这表明粗针活检是获得可手术乳腺癌组织学诊断的一种安全方法。此外，当确定两组肿瘤的受体状态时，雌激素受体阳性肿瘤的百分比以及平均受体值均无差异。然而，粗针活检组中孕激素受体阳性肿瘤更多，这表明可能提交了更好的肿瘤样本进行分析。这可能是使用粗针活检诊断乳腺癌的又一个优势。
