Hansell D T, Davies J W, Burns H J
Br J Surg. 1986 Aug;73(8):659-62. doi: 10.1002/bjs.1800730828.
There are frequent reports that cancer causes an increase in resting energy expenditure (REE), and the presence of hepatic metastases is said to increase REE further. The effect of tumour burden on REE has been measured in 24 patients before and following surgery for colorectal cancer. Fifteen patients had a 'curative' resection whereas nine patients were found to have hepatic metastases at the time of surgery. No significant differences in REE were found between the groups either before surgery or at follow-up, by which time all 15 curative resection patients were tumour free and the remaining nine had progression of their hepatic disease. It is concluded that neither surgical removal of the primary tumour nor progression of metastatic hepatic disease significantly alters REE in patients with colorectal cancer.
经常有报告称癌症会导致静息能量消耗（REE）增加，并且据说肝转移的存在会进一步增加REE。在24例接受结直肠癌手术的患者术前和术后测量了肿瘤负荷对REE的影响。15例患者进行了“根治性”切除，而9例患者在手术时被发现有肝转移。两组在术前或随访时REE均无显著差异，此时所有15例根治性切除患者均无肿瘤，其余9例肝疾病进展。结论是，结直肠癌患者无论是原发性肿瘤的手术切除还是转移性肝病的进展均不会显著改变REE。
