Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, New Delhi.
Department of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi. Correspondence to: Dr Aashima Dabas, Associate Professor, Department of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi.
Indian Pediatr. 2023 Jul 15;60(7):581-584.
The rising trends of obesity, metabolic syndrome and diabetes in adults are worrisome globally. The majority of antecedents to adult non-communicable diseases begin in childhood. Type 2 diabetes is recognized as one of the major diseases that contribute to the NCD burden in childhood. Recently, the US Preventive Services Task Force (USPSTF) and the International Society for Pediatric and Adolescent Diabetes (ISPAD) released their guidelines on diagnosis and management of prediabetes and diabetes in children targeted screening for youth-onset type 2 diabetes is suggested in at-risk children (obese, positive family history of type 2 diabetes, etc.), while the role of screening asymptomatic children is not substantiated. Obesity and insulin resistance are important risk factors for type 2 diabetes. The cutoffs of fasting plasma glucose for the diagnosis of prediabetes and diabetes are >100 to 125 and ≥126 mg/dL, respectively. This update briefly summarizes the recommendations on screening for youth-onset prediabetes and type 2 diabetes.
成年人中肥胖、代谢综合征和糖尿病发病率不断上升，这在全球范围内令人担忧。大多数成人非传染性疾病的病因都始于儿童期。2 型糖尿病是导致儿童期非传染性疾病负担的主要疾病之一。最近，美国预防服务工作组 (USPSTF) 和国际儿科和青少年糖尿病协会 (ISPAD) 发布了儿童期糖尿病和糖尿病前期诊断和管理指南，建议对有风险的儿童（肥胖、2 型糖尿病家族史阳性等）进行青年起病 2 型糖尿病的针对性筛查，而无症状儿童的筛查作用尚未得到证实。肥胖和胰岛素抵抗是 2 型糖尿病的重要危险因素。空腹血糖诊断糖尿病前期和糖尿病的切点分别为>100 至 125 和≥126mg/dL。本更新简要总结了青年起病糖尿病前期和 2 型糖尿病的筛查建议。
