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一名儿童在无多系统炎症综合征的情况下感染新型冠状病毒后出现全葡萄膜炎和视神经病变。

Panuveitis and optic neuropathy following SARS-COV-2 in the absence of multisystem inflammatory syndrome in a child.

作者信息

Land Preston, Shah Veeral, Lovell Daniel J, Miraldi Utz Virginia

机构信息

Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

University of Cincinnati Department of Ophthalmology, Cincinnati, OH, USA.

出版信息

Am J Ophthalmol Case Rep. 2023 Jun 29;32:101876. doi: 10.1016/j.ajoc.2023.101876. eCollection 2023 Dec.

DOI:10.1016/j.ajoc.2023.101876
PMID:37425218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10328812/
Abstract

PURPOSE

To describe the presentation of a healthy 8-year-old female referred to a pediatric ophthalmology clinic with blurred vision and concern for bilateral uveitis.

OBSERVATIONS

The patient was diagnosed with COVID-19 two weeks prior to the onset of ocular symptoms. An examination revealed bilateral pan-uveitis and patient underwent an extensive work-up for an underlying cause that was unremarkable. Two years following the initial presentation, she has not had any evidence of recurrence.

CONCLUSIONS AND IMPORTANCE

This case highlights the potential for COVID-19 to be temporally associated with ocular inflammation and underscores the importance of recognizing and investigating such manifestations in pediatric patients. The mechanism by which COVID-19 may lead to an immune response that affects the eyes is not fully understood, but it is believed to be related to an overactive immune response triggered by the virus. Further studies are needed to better understand the potential relationship between COVID-19 and ocular manifestations in pediatric patients.

摘要

目的

描述一名8岁健康女性因视力模糊并疑似双侧葡萄膜炎转诊至儿科眼科诊所的情况。

观察结果

该患者在眼部症状出现前两周被诊断为新冠病毒肺炎。检查发现双侧全葡萄膜炎,患者接受了全面检查以寻找潜在病因,但未发现异常。首次就诊两年后,她没有任何复发迹象。

结论与重要性

本病例突出了新冠病毒肺炎可能与眼部炎症存在时间关联,并强调了在儿科患者中识别和调查此类表现的重要性。新冠病毒肺炎导致影响眼睛的免疫反应的机制尚未完全明确,但据信与病毒引发的过度免疫反应有关。需要进一步研究以更好地理解新冠病毒肺炎与儿科患者眼部表现之间的潜在关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/4b302045a72a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/c6951bfa2943/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/aa3a221a30ce/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/4b302045a72a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/c6951bfa2943/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/aa3a221a30ce/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10328812/4b302045a72a/gr3.jpg

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