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伴有耳鼻喉表现的儿童期起病复发性多软骨炎

Pediatric-Onset Relapsing Polychondritis With Otolaryngeal Manifestations.

作者信息

Figaro Nicholas J, Figaro Keegan A, Juman Jibran S, Arozarena Rodolfo, Davis King Keisha, Juman Solaiman

机构信息

Otolaryngology-Head and Neck Surgery, Eric Williams Medical Sciences Complex, Champ Fleurs, TTO.

Medicine, Eric Williams Medical Sciences Complex, Champ Fleurs, TTO.

出版信息

Cureus. 2023 Jun 7;15(6):e40085. doi: 10.7759/cureus.40085. eCollection 2023 Jun.

DOI:10.7759/cureus.40085
PMID:37425495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10327613/
Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease that can present with various clinical manifestations. Among the affected sites, the ear, nose, and throat cartilages are frequently involved, often leading to subtle and episodic symptoms that can be challenging to diagnose. A high index of suspicion is necessary for the early identification of these subtle signs, which can aid in early diagnosis and prompt management. In this report, we present a rare case of pediatric-onset relapsing polychondritis that was initially misdiagnosed as laryngotracheobronchitis.

摘要

复发性多软骨炎(RP)是一种罕见的自身免疫性疾病,可表现出多种临床表现。在受累部位中,耳、鼻和喉软骨经常受累,常导致细微且反复发作的症状,诊断颇具挑战性。对于这些细微体征的早期识别,高度的怀疑指数很有必要,这有助于早期诊断和及时治疗。在本报告中,我们呈现了一例罕见的儿童期起病的复发性多软骨炎病例,该病例最初被误诊为喉气管支气管炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/617df6cd7ac4/cureus-0015-00000040085-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/76cade28d848/cureus-0015-00000040085-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/c04a49ad185d/cureus-0015-00000040085-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/2509f74668c6/cureus-0015-00000040085-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/7ba3c82803d3/cureus-0015-00000040085-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/617df6cd7ac4/cureus-0015-00000040085-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/76cade28d848/cureus-0015-00000040085-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/c04a49ad185d/cureus-0015-00000040085-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/2509f74668c6/cureus-0015-00000040085-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/7ba3c82803d3/cureus-0015-00000040085-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff9/10327613/617df6cd7ac4/cureus-0015-00000040085-i05.jpg

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本文引用的文献

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BMJ Case Rep. 2021 Aug 11;14(8):e239774. doi: 10.1136/bcr-2020-239774.
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Relapsing polychondritis in children: A review.儿童复发性多软骨炎:综述。
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Medicine (Baltimore). 2024 Oct 11;103(41):e40106. doi: 10.1097/MD.0000000000040106.
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Relapsing Polychondritis: An Updated Review.复发性多软骨炎:最新综述
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Sudden Respiratory Failure due to Tracheobronchomalacia by Relapsing Polychondritis, Successfully Rescued by Multiple Metallic Stenting and Tracheostomy.复发性多软骨炎所致气管支气管软化症引发的急性呼吸衰竭,经多次金属支架置入及气管切开术成功救治。
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A Case of Relapsing Polychondritis Initiating with Unexplained Fever.一例以不明原因发热起病的复发性多软骨炎病例。
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Critical airway involvement in relapsing polychondritis.复发性多软骨炎中严重气道受累情况
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