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从心脏谜团到牙科发现:解决人工心脏瓣膜患者的反复感染问题

From Cardiac Mystery to Dental Discovery: Resolving Recurrent Infection in a Prosthetic Heart Valve Patient.

作者信息

Nabhan Elias, Kawas Marie-Michelle, Tohme Rana, Nasr Samer R

机构信息

Cardiology Division, University of Balamand, Beirut, LBN.

General Medicine, University of Balamand, Beirut, LBN.

出版信息

Cureus. 2023 Jun 7;15(6):e40073. doi: 10.7759/cureus.40073. eCollection 2023 Jun.

DOI:10.7759/cureus.40073
PMID:37425519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10326637/
Abstract

We present the case of a 71-year-old female with a history of surgical bioprosthetic aortic valve replacement who developed a liquefactive abscess near the mitral valve trigone following Streptococcus gallolyticus bacteremia. The patient initially presented with dyspnea and symptoms of an upper respiratory tract infection. A trans-esophageal echocardiogram revealed mitral valve vegetation and a possible source of sepsis near the prosthetic aortic valve. However, it was the identification of multiple silent dental abscesses during a routine dental check-up that led to the resolution of the patient's symptoms and the eradication of the infectious process. This case highlights the importance of considering dental infections as a potential cause of recurrent bacteremia and infectious complications in patients with prosthetic heart valves.

摘要

我们报告了一例71岁女性患者,该患者有外科生物人工主动脉瓣置换史,在解脲链球菌菌血症后,二尖瓣三角区附近出现液化性脓肿。患者最初表现为呼吸困难和上呼吸道感染症状。经食管超声心动图显示二尖瓣赘生物以及人工主动脉瓣附近可能的脓毒症来源。然而,正是在常规牙科检查中发现的多个无症状牙脓肿,使得患者症状得以缓解,感染过程得以根除。该病例强调了将牙科感染视为人工心脏瓣膜患者复发性菌血症和感染性并发症潜在原因的重要性。

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Blood culture-negative endocarditis in a reference center: etiologic diagnosis of 348 cases.参考中心的血培养阴性的心内膜炎:348例病例的病因诊断
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Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors ClfA and ClfB, the serine-aspartate repeat protein SdrE and protein A.金黄色葡萄球菌激活人血小板聚集的多种机制:聚集因子ClfA和ClfB、丝氨酸-天冬氨酸重复蛋白SdrE及蛋白A的作用
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