Satti Zain, Khurshid Abaan, Mohammed Rahed, Jose Rejath, Olayode Adewale
School of Medicine, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, USA.
Critical Care Medicine, Mount Sinai Queens Hospital, Queens, USA.
Cureus. 2023 Jun 6;15(6):e40042. doi: 10.7759/cureus.40042. eCollection 2023 Jun.
Malaria has various causative agents that can have a spectrum of disease manifestations, some potentially fatal. Various species have been established as etiologies of malaria, though our understanding of the severity of various species is changing. We present a unique case of malaria that resulted in severe disease, a magnitude rarely seen in previous literature. Our patient was a 35-year-old healthy woman who presented to the emergency department with abdominal pain, nausea, vomiting, and fever. Further workup revealed severe thrombocytopenia with prolonged prothrombin (PT) and partial thromboplastin time (PTT). An initial thick smear failed to detect any species, but a thin smear revealed . The patient's hospital stay was complicated by septic shock requiring intensive care unit (ICU) admission. This unique case represents as the causative agent of severe malaria even in healthy, immunocompetent patients.
疟疾有多种致病原，可导致一系列疾病表现，有些可能致命。尽管我们对不同种类疟疾严重程度的认识在不断变化，但已有多种疟原虫被确认为疟疾的病因。我们报告了一例罕见的疟疾病例，该病例导致了严重疾病，其严重程度在以往文献中很少见。我们的患者是一名35岁的健康女性，因腹痛、恶心、呕吐和发热就诊于急诊科。进一步检查发现严重血小板减少，凝血酶原时间（PT）和部分凝血活酶时间（PTT）延长。初次厚涂片未检测到任何疟原虫种类，但薄涂片显示……患者住院期间并发感染性休克，需要入住重症监护病房（ICU）。这个独特的病例表明，即使在健康、免疫功能正常的患者中，……也是严重疟疾的致病原。 （原文中“but a thin smear revealed.”后面内容缺失，翻译时保留原文状态）
