Mubaraki Adnan A
Department of Medicine, Taif University, Taif, SAU.
Cureus. 2023 Jun 8;15(6):e40127. doi: 10.7759/cureus.40127. eCollection 2023 Jun.
Fluctuating weakness affecting the ocular, bulbar, and/or appendicular muscles is characteristic of myasthenia gravis. Autoimmune components and certain drugs have been implicated in the pathophysiology of this disease. I report a case of chronic migraine in which the patient developed symptoms of myasthenia gravis after using galcanezumab, the recently approved anti-calcitonin gene-related peptide (anti-CGRP). This case shows that anti-CGRP medications could affect the neuromuscular junction and cause such symptoms. Moreover, this case illustrates the clinical approach and management of such a presentation.
波动性肌无力累及眼肌、延髓肌和/或肢体肌肉是重症肌无力的特征。自身免疫成分和某些药物与该疾病的病理生理学有关。我报告一例慢性偏头痛病例，该患者在使用最近获批的抗降钙素基因相关肽（anti-CGRP）药物加卡尼单抗后出现了重症肌无力症状。该病例表明，抗CGRP药物可能影响神经肌肉接头并引发此类症状。此外，该病例还阐述了这种临床表现的临床处理方法。
