Melillo Joseph, Patel Keyur, White Christian
New Jersey Institute for Successful Aging, Rowan-Virtua School of Osteopathic Medicine, Stratford, USA.
Cureus. 2023 Jun 8;15(6):e40118. doi: 10.7759/cureus.40118. eCollection 2023 Jun.
Frontotemporal dementia is a neurocognitive disorder that affects language, behavior, or executive functioning. This disease includes a spectrum of presentations that includes multiple variants. The phenocopy syndrome of the behavioral variant of frontotemporal dementia mimics the behavioral variant of frontotemporal dementia. Patients with this condition show a decline in personality, social conduct, and cognitive ability but often display no signs of neurological imaging and exhibit slow progression. This case focuses on a now 70-year-old male who has shown signs of behavioral changes with a slowly progressive clinical course and minimal findings on positron emission tomography (PET) scan, but moderate changes seen on MRI. This report details a clinical presentation of an individual potentially with phenocopy syndrome of behavioral variant frontotemporal dementia and provides context to how symptoms can be managed to better help assist patients and their caregivers.
额颞叶痴呆是一种影响语言、行为或执行功能的神经认知障碍。这种疾病包括一系列表现形式，有多种变体。行为变异型额颞叶痴呆的拟表型综合征模仿行为变异型额颞叶痴呆。患有这种疾病的患者会出现人格、社交行为和认知能力下降，但通常没有神经影像学表现，且进展缓慢。本病例聚焦于一名70岁男性，他表现出行为改变的迹象，临床病程进展缓慢，正电子发射断层扫描（PET）显示结果轻微，但磁共振成像（MRI）显示有中度改变。本报告详细描述了一名可能患有行为变异型额颞叶痴呆拟表型综合征患者的临床表现，并提供了如何管理症状以更好地帮助患者及其护理人员的相关背景信息。
