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侵袭性曲霉菌与血管癌：一例肺侵袭性曲霉菌病合并上皮样血管肉瘤病例

The Ominous Aspergillus With Cancer of Blood Vessels: A Case of Invasive Aspergillosis and Epithelioid Angiosarcoma of the Lung.

作者信息

Bhandari Sambhawana, Baral Maun R, Dandwani Mehndi, Sandeep Fnu, Hegde Abhijith

机构信息

Internal Medicine, Danbury Hospital/Nuvance Health, Danbury, USA.

Pathology, Danbury Hospital/Nuvance Health, Danbury, USA.

出版信息

Cureus. 2023 Jun 6;15(6):e40034. doi: 10.7759/cureus.40034. eCollection 2023 Jun.

DOI:10.7759/cureus.40034
PMID:37425575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10324290/
Abstract

Invasive aspergillosis occurs in the setting of risk factors such as severe or prolonged neutropenia, defects in cell-mediated immunity, and receipt of immunosuppressive therapy, particularly in patients with graft-versus-host disease (GVHD). Pulmonary epithelioid angiosarcomas (EASs) are rare malignant vascular tumors that are aggressive, frequently metastatic, and associated with a poor prognosis. We describe these two rare conditions occurring concurrently.

摘要

侵袭性曲霉病发生于存在严重或长期中性粒细胞减少、细胞介导免疫缺陷以及接受免疫抑制治疗等危险因素的情况下，尤其是在患有移植物抗宿主病（GVHD）的患者中。肺上皮样血管肉瘤（EAS）是罕见的恶性血管肿瘤，具有侵袭性，常发生转移，且预后不良。我们描述了这两种罕见情况同时发生的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/5b3e05fb78d1/cureus-0015-00000040034-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/e4054139656e/cureus-0015-00000040034-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/57265ba80c66/cureus-0015-00000040034-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/51c16d5f207e/cureus-0015-00000040034-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/0f217e64045d/cureus-0015-00000040034-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/5b3e05fb78d1/cureus-0015-00000040034-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/e4054139656e/cureus-0015-00000040034-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/57265ba80c66/cureus-0015-00000040034-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/51c16d5f207e/cureus-0015-00000040034-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/0f217e64045d/cureus-0015-00000040034-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b35/10324290/5b3e05fb78d1/cureus-0015-00000040034-i05.jpg

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本文引用的文献

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Ann Transl Med. 2021 Jan;9(1):74. doi: 10.21037/atm-20-7441.
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Epithelioid angiosarcoma of the liver: report of two cases and review of the literature.肝脏上皮样血管肉瘤：两例报告并文献复习
Int J Clin Exp Pathol. 2018 Jun 1;11(6):3191-3198. eCollection 2018.
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The clinical spectrum of pulmonary aspergillosis.肺部曲霉菌病的临床谱。
Thorax. 2015 Mar;70(3):270-7. doi: 10.1136/thoraxjnl-2014-206291. Epub 2014 Oct 29.
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Performance of galactomannan, beta-d-glucan, Aspergillus lateral-flow device, conventional culture, and PCR tests with bronchoalveolar lavage fluid for diagnosis of invasive pulmonary aspergillosis.用支气管肺泡灌洗液进行半乳甘露聚糖、β - D - 葡聚糖、曲霉侧流装置、传统培养及PCR检测诊断侵袭性肺曲霉病的性能
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Clinical epidemiology of 960 patients with invasive aspergillosis from the PATH Alliance registry.960 例侵袭性曲霉菌病患者的临床流行病学分析：PATH 联盟注册研究。
J Infect. 2012 Nov;65(5):453-64. doi: 10.1016/j.jinf.2012.08.003. Epub 2012 Aug 13.
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Pulmonary aspergillosis: a clinical review.肺曲霉病：临床综述。
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