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牛源性羟基磷灰石异种移植物在开放性楔形高位胫骨截骨术中用于填充骨缺损的应用。

The use of bovine-derived hydroxyapatite xenograft for defect filling in opening-wedge high tibial osteotomy.

作者信息

Santoso Asep, Utomo Pamudji, Mahyudin Ferdiansyah, Utomo Dwikora N, Budhiparama Nicolaas C, Anwar Iwan B, Sibarani Tangkas, Warman Fanny I

机构信息

Department of Orthopaedic and Traumatology, Sebelas Maret University, - Prof. Dr. R. Soeharso Orthopaedic Hospital, Surakarta, Indonesia.

Department of Orthopaedic and Traumatology, Airlangga University, Dr. Soetomo General Hospital, Surabaya, Indonesia.

出版信息

Ann Med Surg (Lond). 2023 Jun 17;85(7):3339-3346. doi: 10.1097/MS9.0000000000000972. eCollection 2023 Jul.

Abstract

UNLABELLED

High tibial osteotomy is a reliable procedure for the correction of knee varus deformity. An opening-wedge high tibial osteotomy (OW-HTO) is the most popular technique. The results of the bone defect after opening the wedge needed special treatment to ensure bone healing. This study aims to evaluate the use of bovine-derived hydroxyapatite graft for defect filling after OW-HTO.

METHODS

A retrospective study was performed on all patients who received OW-HTO at Prof. Dr R. Soeharso Orthopaedic Hospital from November 2019 to December 2022. A total of 21 patients (24 knees) were included in this study. Clinical dan radiological evaluation was performed on all patients preoperative and postoperatively. The mean of the follow-up period was 12.6 months with a minimum of 4 months follow-up.

RESULTS

Primary medial uni-compartment knee osteoarthritis was the most common diagnosis, with 17 of 24 cases (70.8%). Mechanical axis deviation was changed from 31 mm medial deviation (range: 8-52 mm) to 0.45 mm medial deviation (range: 13 - (-8) mm). The anatomic tibiofemoral angle was corrected from a preoperative mean of 4.7 of varus to a mean of 5.8 of valgus postoperatively. Bone defect height was mean 15.9 mm with a range of 10-23 mm. Bone defect width was mean 46.7 mm (range: 34-60 mm). Hydroxyapatite graft integration with the host bone was found in all patients during the final follow-up period.

CONCLUSIONS

Bovine-derived hydroxyapatite graft is a safe and effective material for bone defect filling in OW-HTO procedures with a high bone union rate.

摘要

未标注

高位胫骨截骨术是矫正膝内翻畸形的可靠手术。开口楔形高位胫骨截骨术(OW-HTO)是最常用的技术。开口楔形截骨后骨缺损的处理结果需要特殊治疗以确保骨愈合。本研究旨在评估牛源羟基磷灰石移植物在OW-HTO术后骨缺损填充中的应用。

方法

对2019年11月至2022年12月在R. Soeharso教授骨科医院接受OW-HTO手术的所有患者进行回顾性研究。本研究共纳入21例患者(24个膝关节)。对所有患者进行术前和术后的临床及影像学评估。随访期平均为12.6个月,最短随访时间为4个月。

结果

原发性内侧单髁膝关节骨关节炎是最常见的诊断,24例中有17例(70.8%)。机械轴偏差从内侧偏差31毫米(范围:8 - 52毫米)变为内侧偏差0.45毫米(范围:13 - (-8)毫米)。解剖学胫股角从术前平均内翻4.7°矫正为术后平均外翻5.8°。骨缺损高度平均为15.9毫米,范围为10 - 23毫米。骨缺损宽度平均为46.7毫米(范围:34 - 60毫米)。在最后随访期,所有患者均发现羟基磷灰石移植物与宿主骨融合。

结论

牛源羟基磷灰石移植物是OW-HTO手术中用于骨缺损填充的安全有效材料,骨愈合率高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ac/10328623/f89f33424e96/ms9-85-3339-g001.jpg

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