Belsey James, Diffo Kaze Arnaud, Jobson Simon, Faulkner James, Maas Stefan, Khakha Raghbir, Wilson Adrian J, Pape Dietrich
Department of Sport, Exercise & Health, University of Winchester, Sparkford Road, Winchester, Hampshire, SO22 4NR, England.
Basingstoke and North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire, RG24 9NA, England.
J Exp Orthop. 2019 Mar 28;6(1):13. doi: 10.1186/s40634-019-0184-6.
The purpose of this study was to compare the stability of medial opening-wedge high tibial osteotomy (MOWHTO) with and without different graft materials. Good clinical and radiological outcomes have been demonstrated when either using or not using graft materials during MOWHTO. Variations in the biomechanical properties of different graft types, regarding the stability they provide a MOWHTO, have not been previously investigated.
A 10 mm biplanar MOWHTO was performed on 15 artificial sawbone tibiae, which were fixed using the Activmotion 2 plate. Five bones had OSferion60 wedges (synthetic group), five had allograft bone wedges (allograft group), and five had no wedges (control group) inserted into the osteotomy gap. Static compression was applied axially to each specimen until failure of the osteotomy. Ultimate load, horizontal and vertical displacements were measured and used to calculate construct stiffness and valgus malrotation of the tibial head.
The synthetic group failed at 6.3 kN, followed by the allograft group (6 kN), and the control group (4.5 kN). The most valgus malrotation of the tibial head was observed in the allograft group (2.6°). The synthetic group showed the highest stiffness at the medial side of the tibial head (9.54 kN·mm), but the lowest stiffness at the lateral side (1.59 kN·mm. The allograft group showed high stiffness on the medial side of the tibial head (7.54 kN·mm) as well as the highest stiffness on the lateral side (2.18 kN·mm).
The use of graft materials in MOWHTO results in superior material properties compared to the use of no graft. The static strength of MOWHTO is highest when synthetic grafts are inserted into the osteotomy gap. Allograft wedges provide higher mechanical strength to a MOWHTO than when no graft used. In comparison to the synthetic grafts, allograft wedges result in the stiffness of the osteotomy being more similar at the medial and lateral cortices.
本研究的目的是比较使用和不使用不同移植材料的内侧开口楔形高位胫骨截骨术(MOWHTO)的稳定性。在MOWHTO过程中,无论是否使用移植材料,都已证明有良好的临床和影像学结果。不同移植类型的生物力学特性在为MOWHTO提供稳定性方面的差异,此前尚未进行过研究。
对15个模拟胫骨锯骨标本进行10毫米双平面MOWHTO,使用Activmotion 2钢板固定。5个标本植入OSferion60楔形物(合成材料组),5个植入同种异体骨楔形物(同种异体移植组),5个未在截骨间隙插入楔形物(对照组)。对每个标本轴向施加静态压缩直至截骨失败。测量极限载荷、水平和垂直位移,并用于计算结构刚度和胫骨头外翻畸形旋转。
合成材料组在6.3 kN时失败,其次是同种异体移植组(6 kN)和对照组(4.5 kN)。同种异体移植组观察到胫骨头最严重的外翻畸形旋转(2.6°)。合成材料组在胫骨头内侧显示出最高刚度(9.54 kN·mm),但在外侧刚度最低(1.59 kN·mm)。同种异体移植组在胫骨头内侧显示出高刚度(7.54 kN·mm),在外侧也显示出最高刚度(2.18 kN·mm)。
与不使用移植材料相比,在MOWHTO中使用移植材料可带来更好的材料性能。当在截骨间隙插入合成移植材料时,MOWHTO的静态强度最高。同种异体骨楔形物为MOWHTO提供的机械强度高于不使用移植材料时。与合成移植材料相比,同种异体骨楔形物使截骨术在内侧和外侧皮质的刚度更相似。