Shrestha Abhigan B, Karki Bikash, Acharya Prakash, Kafley Shashwat, Shrestha Nabaraj, Karki Shailendra, Acharya Surya K
M Abdur Rahim Medical College, Dinajpur.
Kathmandu Medical College, Kathmandu, Nepal.
Ann Med Surg (Lond). 2023 May 22;85(7):3642-3645. doi: 10.1097/MS9.0000000000000918. eCollection 2023 Jul.
Despite the lack of scientific evidence supporting its effectiveness, homeopathic treatment is increasingly being used as a form of alternative medicine, with many people taking homeopathic remedies instead of drug therapies. It is based on the principle of 'like cures like', meaning that a remedy similar to the illness can be used to treat it. However, there have been several reports suggesting the risks of homeopathic remedies, among which homeopathy-induced liver injury is widely discussed. Here, we report a case of a 35-year-old well-oriented male patient with a typical clinical presentation of liver injury as presented by yellowish discoloration of sclera and skin along with generalized body itching following the use of homeopathic medicine for musculoskeletal pain. Laboratory reports of increased liver markers along with bilirubin were also suggestive. Excluding other differentials like viral hepatitis, alcoholic hepatitis, hemochromatosis, Wilson disease, and standard drug and toxin-induced hepatitis, the recent use of homeopathic remedies was a contributing factor in leading to the diagnosis of homeopathy-induced liver injury. He was then treated with the discontinuation of homeopathic medicine and supportive care. This case highlights the need for public awareness of the possible complications such as headache, tiredness, skin eruption, dizziness, bowel dysfunction, allergic reactions to acute pancreatitis, renal failure, neurological dysfunction, possible liver injury, and even mortality in those patients who pursue homeopathic treatments and health care professionals should take this into account when making a differential diagnosis in patients with liver injury.
尽管缺乏科学证据支持顺势疗法的有效性,但它作为一种替代医学形式正越来越多地被使用,许多人服用顺势疗法药物而非药物疗法。它基于“以毒攻毒”的原则,即一种与疾病相似的药物可用于治疗该疾病。然而,已有几份报告指出顺势疗法药物存在风险,其中顺势疗法引起的肝损伤被广泛讨论。在此,我们报告一例35岁定向力良好的男性患者,其在使用顺势疗法药物治疗肌肉骨骼疼痛后,出现了典型的肝损伤临床表现,如巩膜和皮肤发黄以及全身瘙痒。实验室报告显示肝酶和胆红素升高也支持这一诊断。排除其他不同病因,如病毒性肝炎、酒精性肝炎、血色素沉着症、威尔逊病以及标准药物和毒素引起的肝炎后,近期使用顺势疗法药物是导致顺势疗法引起肝损伤诊断的一个因素。随后,他停止服用顺势疗法药物并接受支持性治疗。该病例凸显了提高公众意识的必要性,即对于接受顺势疗法治疗的患者,可能会出现诸如头痛、疲劳、皮疹、头晕、肠道功能障碍、急性胰腺炎过敏反应及肾功能衰竭、神经功能障碍、可能的肝损伤甚至死亡等并发症,医疗保健专业人员在对肝损伤患者进行鉴别诊断时应考虑到这一点。