Cosgrove D M, Chavez A M, Lytle B W, Gill C C, Stewart R W, Taylor P C, Goormastic M, Borsh J A, Loop F D
Circulation. 1986 Sep;74(3 Pt 2):I82-7.
To evaluate the early results of mitral valve reconstruction for mitral insufficiency, 117 consecutive cases were analyzed. Sixty-four (57.7%) of the patients were men, and the mean age was 60 +/- 13 years (range 18 to 85). Eighty-nine (76%) of the patients were in NYHA functional class III or IV preoperatively. The cause of the mitral disease was degenerative in 94 (80%) and rheumatic in 13 (11%) patients. Isolated mitral valve repair was performed in 56 patients (47.9%); the remainder underwent associated procedures that included myocardial revascularization in 38 (32.5%). Ninety-nine (85%) underwent a ring annuloplasty but in only seven (6%) was this the only repair technique. Resection of the posterior leaflet was performed in 41 (35%). There were five operative deaths (4.3%); one (1.8%) occurred after isolated repair and four (6.5%) after repair with associated procedures. All deaths occurred in patients greater than 65 years of age who were in NYHA functional class III or IV. Mean follow-up was 13.5 months (range 1 to 62). Two year actuarial survival was 90.6%. Three patients required reoperation (incidence of 2.5% per patient-year). Two patients sustained embolic events (incidence of 1.6% per patient-year). There were no anticoagulant-related complications. After surgery, 100 survivors (96.2%) were in NYHA functional class I or II.
为评估二尖瓣修复治疗二尖瓣关闭不全的早期效果,对117例连续病例进行了分析。患者中64例(57.7%)为男性,平均年龄60±13岁(范围18至85岁)。89例(76%)患者术前处于纽约心脏协会(NYHA)心功能Ⅲ或Ⅳ级。二尖瓣疾病的病因在94例(80%)患者中为退行性变,13例(11%)为风湿性。56例患者(47.9%)接受了单纯二尖瓣修复术;其余患者接受了相关手术,其中38例(32.5%)进行了心肌血运重建。99例(85%)患者进行了瓣环成形术,但仅7例(6%)将其作为唯一的修复技术。41例(35%)患者进行了后叶切除。有5例手术死亡(4.3%);1例(1.8%)发生在单纯修复术后,4例(6.5%)发生在联合相关手术修复术后。所有死亡均发生在年龄大于65岁、NYHA心功能Ⅲ或Ⅳ级的患者中。平均随访时间为13.5个月(范围1至62个月)。两年实际生存率为90.6%。3例患者需要再次手术(发生率为每年2.5%/患者)。2例患者发生栓塞事件(发生率为每年1.6%/患者)。无抗凝相关并发症。术后,100例幸存者(96.2%)处于NYHA心功能Ⅰ或Ⅱ级。