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二尖瓣重建的结果。布鲁塞尔自由大学埃拉斯穆斯医院的经验。

Results of mitral valve reconstruction. Experience of Hôpital Erasme, ULB, Brussels.

作者信息

Huynh C H, De Smet J M, Joris M, Le Clerc J L

机构信息

Department of Cardiac Surgery, Hôpital Erasme, ULB, Brussels, Belgium.

出版信息

Acta Chir Belg. 1995 May-Jun;95(3):123-6.

PMID:7610741
Abstract

BACKGROUND

Reconstructive surgery of the mitral valve has been an alternative to mitral valve replacement in patients with mitral regurgitation. In order to evaluate the early results of mitral valve reconstruction, 38 consecutive cases were analyzed.

METHODS

Between January 1985 and May 1993, 38 patients with mitral valve incompetence were treated with a system of reconstructive techniques. Nineteen (52%) of the patients were in NYHA functional class II and seventeen (45%) in class III or IV preoperatively. The cause of the mitral disease was degenerative in 25 (66%), rheumatic in 6 (15%) and ischaemic in 5 (13%) patients. Isolated mitral valve repair was performed in 25 patients (66%); the remainder underwent associated procedures that included a myocardial revascularization in 9 patients (23.6%). Thirty-eight patients (100%) underwent a ring annuloplasty. Resection of the posterior leaflet was performed in 24 patients (63%).

RESULTS

There was one operative death (2.6%) and two late deaths (5.3%). Postoperatively, four patients sustained embolic events (incidence 10.5%). Six patients (15.8%) were precociously reoperated within the following month; two patients required valve replacement, one had mediastinitis and three other ones needed a pericardial drainage. Patients routinely received acenocoumarol anticoagulation for two months. Mean follow-up was 33 months (range 6 to 104) and one patient was lost to follow-up. Two years actuarial survival was 91.4%. There were no thromboembolic complications in the follow-up period. No patient was reoperated for valvular insufficiency beyond this time limit. One patient had late endocarditis and has been reoperated for mitral replacement (2.6%). After surgery, 34 survivors (89.5%) were in the NYHA functional class I or II.

CONCLUSIONS

These results demonstrate that mitral valvuloplasty is associated with lower operative mortality rates. Preservation of the mitral valve mechanism raised the performance of the left ventricle after reconstructive surgery. The incidence of reoperation and thromboembolism was low.

摘要

背景

二尖瓣重建手术已成为二尖瓣反流患者二尖瓣置换术的替代选择。为评估二尖瓣重建的早期结果,对连续38例病例进行了分析。

方法

1985年1月至1993年5月期间,38例二尖瓣关闭不全患者接受了重建技术系统治疗。术前,19例(52%)患者为纽约心脏协会(NYHA)心功能II级,17例(45%)为III级或IV级。二尖瓣疾病的病因在25例(66%)患者中为退行性病变,6例(15%)为风湿性病变,5例(13%)为缺血性病变。25例患者(66%)接受了单纯二尖瓣修复;其余患者接受了相关手术,其中9例(23.6%)患者进行了心肌血运重建。38例患者(100%)接受了瓣环成形术。24例患者(63%)进行了后叶切除。

结果

有1例手术死亡(2.6%)和2例晚期死亡(5.3%)。术后,4例患者发生栓塞事件(发生率10.5%)。6例患者(15.8%)在接下来的一个月内提前再次手术;2例患者需要进行瓣膜置换,1例发生纵隔炎,另外3例需要进行心包引流。患者常规接受醋硝香豆素抗凝治疗两个月。平均随访时间为33个月(范围6至104个月),1例患者失访。两年的预期生存率为91.4%。随访期间无血栓栓塞并发症。在此时间限制之后,没有患者因瓣膜功能不全再次手术。1例患者发生晚期心内膜炎,已接受二尖瓣置换再次手术(2.6%)。术后,34例幸存者(89.5%)为NYHA心功能I级或II级。

结论

这些结果表明二尖瓣成形术的手术死亡率较低。保留二尖瓣机制提高了重建手术后左心室的功能。再次手术和血栓栓塞的发生率较低。

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