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肉瘤手术的 10 项建议:基于德国 S3 指南“成人软组织肉瘤”的外科协会共识。

Ten recommendations for sarcoma surgery: consensus of the surgical societies based on the German S3 guideline "Adult Soft Tissue Sarcomas".

机构信息

Sarcoma Unit, Department of Surgery and Mannheim Cancer Center, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68135, Mannheim, Germany.

Department of Orthopedics and Trauma, Medical University of Graz, Graz, Austria.

出版信息

Langenbecks Arch Surg. 2023 Jul 11;408(1):272. doi: 10.1007/s00423-023-03002-3.

DOI:10.1007/s00423-023-03002-3
PMID:37430129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10333354/
Abstract

PURPOSE

The evidence-based (S3) guideline "Adult Soft Tissue Sarcomas" (AWMF Registry No. 032/044OL) published by the German Guideline Program in Oncology (GGPO) covers all aspects of sarcoma treatment with 229 recommendations. Representatives of all medical specialties involved in sarcoma treatment contributed to the guideline. This paper compiles the most important recommendations for surgeons selected by delegates from the surgical societies.

METHODS

A Delphi process was used. Delegates from the surgical societies involved in guideline process selected the 15 recommendations that were most important to them. Votes for similar recommendations were tallied. From the resulting ranked list, the 10 most frequently voted recommendations were selected and confirmed by consensus in the next step.

RESULTS

The statement "Resection of primary soft tissue sarcomas of the extremities should be performed as a wide resection. The goal is an R0 resection" was selected as the most important term. The next highest ranked recommendations were the need for a preoperative biopsy, performing preoperative MRI imaging with contrast, and discussing all cases before surgery in a multidisciplinary sarcoma committee.

CONCLUSION

The evidence-based guideline "Adult Soft Tissue Sarcomas" is a milestone to improve the care of sarcoma patients in Germany. The selection of the top ten recommendations by surgeons for surgeons has the potential to improve the dissemination and acceptance of the guideline and thus improve the overall outcome of sarcoma patients.

摘要

目的

德国肿瘤学会指南项目(GGPO)发布的循证(S3)指南“成人软组织肉瘤”(AWMF 注册号 032/044OL)涵盖了肉瘤治疗的各个方面,共包含 229 条建议。参与肉瘤治疗的所有医学专业的代表都为该指南做出了贡献。本文编译了外科医生代表从外科协会中选择的最重要的建议。

方法

使用 Delphi 法。参与指南制定过程的外科协会代表选择了他们认为最重要的 15 条建议。对类似建议的投票进行了汇总。根据由此产生的排名列表,选择了前 10 条被投票最多的建议,并在下一阶段通过共识进行了确认。

结果

“四肢原发性软组织肉瘤的切除应作为广泛切除进行。目标是达到 R0 切除”这一说法被选为最重要的术语。排名第二的建议是需要进行术前活检、进行术前 MRI 成像(含对比剂),以及在多学科肉瘤委员会中讨论所有病例。

结论

循证指南“成人软组织肉瘤”是改善德国肉瘤患者治疗的一个里程碑。外科医生为外科医生选择的十大建议具有提高指南的传播和接受程度的潜力,从而改善肉瘤患者的整体预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe94/10333354/ca4adc5b75cb/423_2023_3002_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe94/10333354/b5efe14669a4/423_2023_3002_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe94/10333354/ca4adc5b75cb/423_2023_3002_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe94/10333354/b5efe14669a4/423_2023_3002_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe94/10333354/ca4adc5b75cb/423_2023_3002_Fig2_HTML.jpg

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