鲨鱼（灰真鲨）弹性硬蛋白：其胶原蛋白作为[α1（E）]3同三聚体的特性

Shark (Prionace glauca) elastoidin: characterization of its collagen as [alpha 1(E)]3 homotrimers.

作者信息

Kimura S, Uematsu Y, Miyauchi Y

出版信息

Comp Biochem Physiol B. 1986;84(3):305-8. doi: 10.1016/0305-0491(86)90081-7.

Abstract

A new type of collagen was isolated from elastoidin of great blue shark by limited pepsin digestion. The collagen alpha chain of elastoidin, designated alpha 1(E), was very similar in electrophoretic and chromatographic behavior and amino acid composition to shark skin alpha 1(I) chain, but they were genetically-distinct on the basis of CNBr-peptide maps. The collagen molecule of elastoidin was shown to be an [alpha 1(E)]3 homotrimer.

摘要

通过有限的胃蛋白酶消化，从大青鲨的弹性硬蛋白中分离出一种新型胶原蛋白。弹性硬蛋白的胶原蛋白α链，命名为α1(E)，在电泳、色谱行为和氨基酸组成上与鲨鱼皮α1(I)链非常相似，但根据溴化氰肽图谱，它们在基因上是不同的。弹性硬蛋白的胶原分子被证明是一种[α1(E)]3同三聚体。