Department of Physical Therapy, Faculty of Nursing and Rehabilitation, Konan Women's University, 6-2-13 Morikita-machi, Higashinada-ku, Kobe 658-0001, Hyogo, Japan.
Department of Rehabilitation, Fukuoka Orthopaedic Hospital, 2-10-50 Yanagochi, Minami-ku, Fukuoka 815-0063, Fukuoka, Japan.
Sensors (Basel). 2023 May 9;23(10):4578. doi: 10.3390/s23104578.
This study aimed to assess the association between the degree of varus thrust (VT) assessed by an inertial measurement unit (IMU) and patient-reported outcome measures (PROMs) in patients with knee osteoarthritis. Seventy patients (mean age: 59.8 ± 8.6 years; women: n = 40) were instructed to walk on a treadmill with an IMU attached to the tibial tuberosity. For the index of VT during walking (VT-index), the swing-speed adjusted root mean square of acceleration in the mediolateral direction was calculated. As the PROMs, the Knee Injury and Osteoarthritis Outcome Score were used. Data on age, sex, body mass index, static alignment, central sensitization, and gait speed were collected as potential confounders. After adjusting for potential confounders, multiple linear regression analysis revealed that the VT-index was significantly associated with the pain score (standardized β = -0.295; = 0.026), symptoms score (standardized β = -0.287; = 0.026), and activities of the daily living score (standardized β = -0.256; = 0.028). Our results indicated that larger VT values during gait are associated with worse PROMs, suggesting that an intervention to reduce VT might be an option for clinicians trying to improve PROMs.
本研究旨在评估惯性测量单元 (IMU) 评估的内翻推力 (VT) 程度与膝骨关节炎患者的患者报告结局测量 (PROM) 之间的关联。70 名患者（平均年龄：59.8 ± 8.6 岁；女性：n = 40）被指示在安装有 IMU 的跑步机上行走。对于行走时的 VT 指数（VT-index），计算了在横方向上的加速度的摆动速度调整均方根。作为 PROM，使用膝关节损伤和骨关节炎结果评分。收集了年龄、性别、体重指数、静态对线、中枢敏化和步态速度等数据作为潜在混杂因素。在调整潜在混杂因素后，多元线性回归分析显示 VT-index 与疼痛评分（标准化 β = -0.295；p = 0.026）、症状评分（标准化 β = -0.287；p = 0.026）和日常生活活动评分（标准化 β = -0.256；p = 0.028）显著相关。我们的结果表明，行走时更大的 VT 值与更差的 PROM 相关，这表明减少 VT 的干预措施可能是临床医生试图改善 PROM 的一种选择。
