Bierman M I, Brown M, Muren O, Keenan R L, Glauser F L
Crit Care Med. 1986 Sep;14(9):832-3. doi: 10.1097/00003246-198609000-00017.
We report a case of status asthmaticus that was unresponsive to the usual agents. The use of an inhalational anesthetic agent allowed us to ventilate the patient with lower inspiratory pressures; however, lasting improvement did not occur until she mobilized large quantities of secretions. To our knowledge, this is the first clinical report on the use of isoflurane anesthesia to treat severe asthma. Despite prolonged administration, there were no significant side-effects. This case demonstrates both the benefits and limitations of such therapy.
我们报告了一例对常规药物无反应的哮喘持续状态病例。使用吸入性麻醉剂使我们能够以较低的吸气压力为患者通气；然而，直到她咳出大量分泌物后才出现持久改善。据我们所知，这是关于使用异氟烷麻醉治疗重度哮喘的首例临床报告。尽管给药时间较长，但未出现明显副作用。该病例展示了这种治疗方法的益处和局限性。
