Jaiswal Pooja, Goyal Rohit, Dubey Chanda, Akhter Javed, Ramalingam Karthikeyan, Kalita Sangita
Oral and Maxillofacial Surgery, Maharaja Ganga Singh Dental College and Research Centre, Sriganganagar, IND.
Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2023 Jun 9;15(6):e40167. doi: 10.7759/cureus.40167. eCollection 2023 Jun.
Aim The study compared the anesthetic effectiveness of articaine and lignocaine when premolars are extracted bilaterally for orthodontic purposes. Material and methods This prospective split-mouth study was performed on 30 cases selected from orthodontic referral patients reporting to the Oral and Maxillofacial Surgery Department at Maharaja Ganga Singh Dental College and Research Center, Rajasthan, India, for bilateral extraction of premolars under local anesthesia. We used 4% articaine hydrochloride and adrenaline 1:100000 (AH) as group A and 2% lignocaine hydrochloride with adrenaline 1:100000 (LH) on the control side as group B. For premolar anesthetization, 0.6-1.6 ml of AH and 1-2 ml of LH were injected submucosally in the buccal vestibular area. The extraction procedure was then carried out after achieving adequate anesthesia. The pain was assessed with Visual Analog Scale. The average onset time and duration of anesthesia were recorded. Data collected were summarized with descriptive statistics. The SPSS version 23.0 (IBM Corp., Armonk, New York) was used for data entry, validation, and analysis. Means of continuous variables were compared using the student t-test. All tests were 2-tailed and significant at equal or less than 0.05. (p≤0.05). Results When comparing the overall anesthetic efficiency, Group A had a lower overall pain score of 0.43 while Group B had a higher overall pain score of 2.9. The average onset time of anesthesia in Group A was 1.2 minutes and 2.55 minutes in Group B. In Group A, the average duration of anesthesia was 70 minutes, and 46.5 minutes in Group B. These parameters were statistically significant with a p-value of <0.05. Conclusion The study concluded that as an alternative to lignocaine, articaine could be used effectively for maxillary premolar extractions for orthodontic reasons obviating palatal injection which is very painful to the patient.
本研究比较了阿替卡因和利多卡因在双侧拔除前磨牙用于正畸目的时的麻醉效果。
本前瞻性双侧对照研究选取了30例正畸转诊患者，这些患者前往印度拉贾斯坦邦甘加·辛格王公牙科学院及研究中心口腔颌面外科，在局部麻醉下双侧拔除前磨牙。我们将4%盐酸阿替卡因和1:100000肾上腺素（AH）作为A组，对照侧使用2%盐酸利多卡因和1:100000肾上腺素（LH）作为B组。在前磨牙麻醉时，在颊侧前庭区黏膜下注射0.6 - 1.6 ml的AH和1 - 2 ml的LH。在达到充分麻醉后进行拔牙操作。使用视觉模拟量表评估疼痛程度。记录麻醉的平均起效时间和持续时间。收集的数据用描述性统计进行总结。使用SPSS 23.0版（IBM公司，纽约州阿蒙克）进行数据录入、验证和分析。连续变量的均值使用学生t检验进行比较。所有检验均为双侧检验，显著性水平为等于或小于0.05（p≤0.05）。
在比较总体麻醉效果时，A组的总体疼痛评分较低，为0.43，而B组的总体疼痛评分较高，为2.9。A组麻醉的平均起效时间为1.2分钟，B组为2.55分钟。A组麻醉的平均持续时间为70分钟，B组为46.5分钟。这些参数具有统计学显著性，p值<0.05。
本研究得出结论，作为利多卡因的替代品，阿替卡因可有效用于正畸原因的上颌前磨牙拔除，避免了对患者非常痛苦的腭部注射。
