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一项比较4%阿替卡因颊侧浸润与2%利多卡因颊侧及腭侧浸润用于拔除上颌前磨牙的随机对照试验。

A Randomized Control Trial Comparing Buccal Infiltration of 4% Articaine with Buccal and Palatal Infiltration of 2% Lignocaine for the Extraction of Maxillary Premolar Teeth.

作者信息

Sandilya Vikas, Andrade Neelam Noel, Mathai Paul C, Aggarwal Neha, Sahu Vyankatesh, Nerurkar Shibani

机构信息

Department of Oral and Maxillofacial Surgery, Nair Hospital Dental College, Mumbai, Maharashtra, India.

出版信息

Contemp Clin Dent. 2019 Apr-Jun;10(2):284-288. doi: 10.4103/ccd.ccd_529_18.

Abstract

INTRODUCTION

The use of articaine has been claimed to obviate the need for routine palatal local anesthetic injections on account of its better diffusion through soft and hard tissues as compared to other local anesthetic agents.

OBJECTIVE

The objective of the study is to evaluate the efficacy of 4% articaine (with 1:100,000 adrenaline) infiltrated only buccally in the extraction of maxillary premolars for orthodontic reasons.

MATERIALS AND METHODS

A double-blind randomized clinical trial with a split-mouth design, where each patient ( = 100) was part of two groups, was conducted. Experimental Group 1: single buccal infiltration of 4% articaine with 1:100,000 adrenaline (Septanest™ with adrenaline 1:100,000 by Septodont). Control Group 2: routine buccal and palatal infiltrations of 2% lignocaine with 1:200,000 adrenaline (Lox™ 2% with adrenaline 1:200,000 by Neon). The parameters studied were time to onset of anesthesia, pain during the extraction procedure (not during the injecting of the local anesthetic), and frequency of extra amount of local anesthetic injected.

RESULTS

The difference was not statistically significant ( > 0.05) between the two groups with respect to all three parameters. This proves that a single buccal infiltration of articaine can be used as an alternative to lignocaine for the extraction of the maxillary premolar teeth in most of the cases.

CONCLUSION

This proves that a single buccal infiltration of articaine can be used as an alternative to lignocaine for the extraction of the maxillary premolar teeth in most of the cases.

摘要

引言

由于阿替卡因相较于其他局部麻醉剂在软组织和硬组织中具有更好的扩散性,因此有人声称使用阿替卡因无需进行常规的腭部局部麻醉注射。

目的

本研究的目的是评估仅在颊侧注射4%阿替卡因(含1:100,000肾上腺素)用于正畸原因拔除上颌前磨牙的疗效。

材料与方法

采用双盲随机临床试验,采用分口设计,每位患者(n = 100)分为两组。实验组1:单次颊侧注射4%阿替卡因与1:100,000肾上腺素(Septodont公司的含1:100,000肾上腺素的Septanest™)。对照组2:常规颊侧和腭侧注射2%利多卡因与1:200,000肾上腺素(Neon公司的含1:200,000肾上腺素的Lox™ 2%)。研究的参数包括麻醉起效时间、拔牙过程中的疼痛(而非局部麻醉注射时的疼痛)以及额外注射局部麻醉剂的频率。

结果

两组在所有三个参数方面的差异均无统计学意义(P > 0.05)。这证明在大多数情况下,单次颊侧注射阿替卡因可作为利多卡因的替代方法用于拔除上颌前磨牙。

结论

这证明在大多数情况下,单次颊侧注射阿替卡因可作为利多卡因的替代方法用于拔除上颌前磨牙。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/7145254/df5b44dc7ee1/CCD-10-284-g001.jpg

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