• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项比较4%阿替卡因颊侧浸润与2%利多卡因颊侧及腭侧浸润用于拔除上颌前磨牙的随机对照试验。

A Randomized Control Trial Comparing Buccal Infiltration of 4% Articaine with Buccal and Palatal Infiltration of 2% Lignocaine for the Extraction of Maxillary Premolar Teeth.

作者信息

Sandilya Vikas, Andrade Neelam Noel, Mathai Paul C, Aggarwal Neha, Sahu Vyankatesh, Nerurkar Shibani

机构信息

Department of Oral and Maxillofacial Surgery, Nair Hospital Dental College, Mumbai, Maharashtra, India.

出版信息

Contemp Clin Dent. 2019 Apr-Jun;10(2):284-288. doi: 10.4103/ccd.ccd_529_18.

DOI:10.4103/ccd.ccd_529_18
PMID:32308291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7145254/
Abstract

INTRODUCTION

The use of articaine has been claimed to obviate the need for routine palatal local anesthetic injections on account of its better diffusion through soft and hard tissues as compared to other local anesthetic agents.

OBJECTIVE

The objective of the study is to evaluate the efficacy of 4% articaine (with 1:100,000 adrenaline) infiltrated only buccally in the extraction of maxillary premolars for orthodontic reasons.

MATERIALS AND METHODS

A double-blind randomized clinical trial with a split-mouth design, where each patient ( = 100) was part of two groups, was conducted. Experimental Group 1: single buccal infiltration of 4% articaine with 1:100,000 adrenaline (Septanest™ with adrenaline 1:100,000 by Septodont). Control Group 2: routine buccal and palatal infiltrations of 2% lignocaine with 1:200,000 adrenaline (Lox™ 2% with adrenaline 1:200,000 by Neon). The parameters studied were time to onset of anesthesia, pain during the extraction procedure (not during the injecting of the local anesthetic), and frequency of extra amount of local anesthetic injected.

RESULTS

The difference was not statistically significant ( > 0.05) between the two groups with respect to all three parameters. This proves that a single buccal infiltration of articaine can be used as an alternative to lignocaine for the extraction of the maxillary premolar teeth in most of the cases.

CONCLUSION

This proves that a single buccal infiltration of articaine can be used as an alternative to lignocaine for the extraction of the maxillary premolar teeth in most of the cases.

摘要

引言

由于阿替卡因相较于其他局部麻醉剂在软组织和硬组织中具有更好的扩散性,因此有人声称使用阿替卡因无需进行常规的腭部局部麻醉注射。

目的

本研究的目的是评估仅在颊侧注射4%阿替卡因(含1:100,000肾上腺素)用于正畸原因拔除上颌前磨牙的疗效。

材料与方法

采用双盲随机临床试验,采用分口设计,每位患者(n = 100)分为两组。实验组1:单次颊侧注射4%阿替卡因与1:100,000肾上腺素(Septodont公司的含1:100,000肾上腺素的Septanest™)。对照组2:常规颊侧和腭侧注射2%利多卡因与1:200,000肾上腺素(Neon公司的含1:200,000肾上腺素的Lox™ 2%)。研究的参数包括麻醉起效时间、拔牙过程中的疼痛(而非局部麻醉注射时的疼痛)以及额外注射局部麻醉剂的频率。

结果

两组在所有三个参数方面的差异均无统计学意义(P > 0.05)。这证明在大多数情况下,单次颊侧注射阿替卡因可作为利多卡因的替代方法用于拔除上颌前磨牙。

结论

这证明在大多数情况下,单次颊侧注射阿替卡因可作为利多卡因的替代方法用于拔除上颌前磨牙。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/7145254/df5b44dc7ee1/CCD-10-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/7145254/df5b44dc7ee1/CCD-10-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/7145254/df5b44dc7ee1/CCD-10-284-g001.jpg

相似文献

1
A Randomized Control Trial Comparing Buccal Infiltration of 4% Articaine with Buccal and Palatal Infiltration of 2% Lignocaine for the Extraction of Maxillary Premolar Teeth.一项比较4%阿替卡因颊侧浸润与2%利多卡因颊侧及腭侧浸润用于拔除上颌前磨牙的随机对照试验。
Contemp Clin Dent. 2019 Apr-Jun;10(2):284-288. doi: 10.4103/ccd.ccd_529_18.
2
Extraction of permanent maxillary teeth by only buccal infiltration of articaine.仅通过阿替卡因颊侧浸润麻醉拔除上颌恒牙
J Maxillofac Oral Surg. 2013 Jun;12(2):130-2. doi: 10.1007/s12663-012-0396-0. Epub 2012 Aug 24.
3
Anesthetic efficacy and safety of 2% lidocaine hydrochloride with 1:100,000 adrenaline and 4% articaine hydrochloride with 1:100,000 adrenaline as a single buccal injection in the extraction of maxillary premolars for orthodontic purposes.2%盐酸利多卡因加1:100,000肾上腺素和4%盐酸阿替卡因加1:100,000肾上腺素作为单一颊侧注射用于正畸目的上颌前磨牙拔除的麻醉效果和安全性。
J Dent Anesth Pain Med. 2020 Aug;20(4):233-240. doi: 10.17245/jdapm.2020.20.4.233. Epub 2020 Aug 27.
4
Comparison of the Efficacy Between Articaine and Lignocaine in Simultaneous Bilateral Orthodontic Maxillary Premolar Extractions: A Split-Mouth Comparative Study.阿替卡因与利多卡因在双侧同时拔除正畸上颌前磨牙中的疗效比较:一项半口对照研究
Cureus. 2023 Dec 6;15(12):e50078. doi: 10.7759/cureus.50078. eCollection 2023 Dec.
5
Anesthetic efficacy of 4% articaine and 2% lignocaine in achieving palatal anesthesia following a single buccal infiltration during periodontal therapy: A randomized double-blind split-mouth study.4%阿替卡因和2%利多卡因在牙周治疗单次颊侧浸润后实现腭部麻醉的麻醉效果:一项随机双盲半口研究。
J Anaesthesiol Clin Pharmacol. 2018 Jan-Mar;34(1):107-110. doi: 10.4103/joacp.JOACP_200_15.
6
A Prospective Study to Assess the Efficacy of 4% Articaine, 0.5% Bupivacaine and 2% Lignocaine using a Single Buccal Supraperiosteal Injection for Maxillary Tooth Extraction.一项前瞻性研究,旨在评估使用单次颊侧骨膜上注射 4% 阿替卡因、0.5% 布比卡因和 2% 利多卡因进行上颌牙拔除术的疗效。
J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S721-S724. doi: 10.4103/jpbs.JPBS_659_20. Epub 2021 Jun 5.
7
A Split-Mouth Clinical Comparative Evaluation of the Anesthetic Efficacy of Articaine and Lignocaine for Maxillary Bicuspids Extraction.阿替卡因和利多卡因在上颌双尖牙拔除术中麻醉效果的分口临床对比评估
Cureus. 2023 Jun 9;15(6):e40167. doi: 10.7759/cureus.40167. eCollection 2023 Jun.
8
Single buccal infiltration of high concentration lignocaine versus articaine in maxillary third molar surgery.在上颌第三磨牙手术中,高浓度利多卡因与阿替卡因单次颊部浸润麻醉的比较
J Dent Anesth Pain Med. 2020 Aug;20(4):203-212. doi: 10.17245/jdapm.2020.20.4.203. Epub 2020 Aug 27.
9
The Effectiveness of Articaine and Lidocaine Single Buccal Infiltration versus Conventional Buccal and Palatal Injection Using Lidocaine during Primary Maxillary Molar Extraction: A Randomized Control Trial.阿替卡因和利多卡因单次颊侧浸润与利多卡因常规颊侧和腭侧注射在上颌乳磨牙拔除术中的有效性:一项随机对照试验
Anesth Essays Res. 2017 Jan-Mar;11(1):160-164. doi: 10.4103/0259-1162.186589.
10
Comparison of articaine and lignocaine for uncomplicated maxillary exodontia.阿替卡因与利多卡因用于单纯性上颌牙拔除术的比较。
J Coll Physicians Surg Pak. 2015 Mar;25(3):181-4.

引用本文的文献

1
Can Single Buccal Infiltration With 4% Articaine Induce Sufficient Analgesia for the Extraction of Maxillary Teeth? A Systematic Literature Review.4%阿替卡因单次颊侧浸润麻醉能否为上颌牙拔除提供足够的镇痛效果?一项系统文献综述。
Cureus. 2023 Aug 5;15(8):e42975. doi: 10.7759/cureus.42975. eCollection 2023 Aug.
2
A Split-Mouth Clinical Comparative Evaluation of the Anesthetic Efficacy of Articaine and Lignocaine for Maxillary Bicuspids Extraction.阿替卡因和利多卡因在上颌双尖牙拔除术中麻醉效果的分口临床对比评估
Cureus. 2023 Jun 9;15(6):e40167. doi: 10.7759/cureus.40167. eCollection 2023 Jun.
3
Physiology of pregnancy and oral local anesthesia considerations.

本文引用的文献

1
Palatal injection for removal of maxillary teeth: is it required? A systematic review.拔除上颌牙时腭部注射是否必要?一项系统评价
Int J Oral Maxillofac Surg. 2016 Oct;45(10):1283-92. doi: 10.1016/j.ijom.2016.05.005. Epub 2016 May 30.
2
Articaine hydrochloride: is it the solution?盐酸阿替卡因:它是解决方案吗?
Dent Update. 2015 Jun;42(5):493. doi: 10.12968/denu.2015.42.5.493.
3
Extraction of permanent maxillary teeth by only buccal infiltration of articaine.仅通过阿替卡因颊侧浸润麻醉拔除上颌恒牙
妊娠生理学与口腔局部麻醉的考虑因素。
PeerJ. 2023 Jun 29;11:e15585. doi: 10.7717/peerj.15585. eCollection 2023.
4
Efficacy of Articaine vs Lignocaine for infiltration anaesthesia during primary molar extractions.阿替卡因与利多卡因用于乳牙拔除浸润麻醉的疗效比较。
Pak J Med Sci. 2022 Mar-Apr;38(4Part-II):1048-1055. doi: 10.12669/pjms.38.4.5343.
5
Articaine use does not routinely eliminate the need for palatal injections for primary maxillary molar extractions: a randomized cross-over clinical trial.阿替卡因的使用并未常规消除上颌第一磨牙拔除时腭侧注射的需要:一项随机交叉临床试验。
Oral Maxillofac Surg. 2022 Dec;26(4):603-611. doi: 10.1007/s10006-021-01021-2. Epub 2021 Dec 1.
6
Can 4% Articaine Buccal Infiltration Replace Inferior Alveolar Nerve Block (IANB) with 2% Xylocaine for Pulp Therapy in Primary Mandibular Molars? A Systematic Review.4%阿替卡因颊部浸润麻醉能否替代2%利多卡因下牙槽神经阻滞麻醉用于乳牙下颌第一磨牙的牙髓治疗?一项系统评价
Int J Clin Pediatr Dent. 2021 May-Jun;14(3):420-425. doi: 10.5005/jp-journals-10005-1974.
7
Can single buccal infiltration with 4% articaine induce sufficient analgesia for the extraction of primary molars in children: a systematic literature review.4%阿替卡因单次颊侧浸润麻醉能否为儿童乳牙拔除提供足够的镇痛效果:一项系统文献综述
J Dent Anesth Pain Med. 2020 Aug;20(4):179-186. doi: 10.17245/jdapm.2020.20.4.179. Epub 2020 Aug 27.
J Maxillofac Oral Surg. 2013 Jun;12(2):130-2. doi: 10.1007/s12663-012-0396-0. Epub 2012 Aug 24.
4
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.一项在下颌牙齿不可逆性牙髓炎患者下颌神经阻滞失败后,不同辅助局部麻醉技术的前瞻性随机试验。
J Endod. 2012 Apr;38(4):421-5. doi: 10.1016/j.joen.2011.12.006. Epub 2012 Feb 2.
5
The pulpal anesthetic efficacy of articaine versus lidocaine in dentistry: a meta-analysis.阿替卡因与利多卡因在牙科牙髓麻醉效果的比较:一项荟萃分析。
J Am Dent Assoc. 2011 May;142(5):493-504. doi: 10.14219/jada.archive.2011.0219.
6
Articaine: a review of the literature.阿替卡因:文献综述。
Br Dent J. 2011 Apr 9;210(7):323-9. doi: 10.1038/sj.bdj.2011.240.
7
Intramolecular hydrogen bonding in articaine can be related to superior bone tissue penetration: a molecular dynamics study.阿替卡因中环上的分子内氢键与其优越的骨组织穿透力有关:一项分子动力学研究。
Biophys Chem. 2011 Feb;154(1):18-25. doi: 10.1016/j.bpc.2010.12.002. Epub 2010 Dec 16.
8
Articaine buccal infiltration enhances the effectiveness of lidocaine inferior alveolar nerve block.阿替卡因颊部浸润可提高利多卡因下牙槽神经阻滞的效果。
Int Endod J. 2009 Mar;42(3):238-46. doi: 10.1111/j.1365-2591.2008.01507.x.
9
Comparison of the efficiencies of permanent maxillary tooth removal performed with single buccal infiltration versus routine buccal and palatal injection.单颊侧浸润麻醉与常规颊侧及腭侧注射麻醉用于上颌恒牙拔除的效率比较
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Mar;107(3):359-63. doi: 10.1016/j.tripleo.2008.08.025. Epub 2008 Nov 8.
10
A prospective, randomized, double-blind comparison of articaine and lidocaine for maxillary infiltrations.阿替卡因与利多卡因用于上颌浸润麻醉的前瞻性、随机、双盲对照研究。
J Endod. 2008 Apr;34(4):389-93. doi: 10.1016/j.joen.2008.01.004. Epub 2008 Feb 7.