Samiei Mohammad, Adibkia Khosro, Ghasemi Negin, Tupal Ayda, Mohaghegh Seraj
Department of Endodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute and Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Iran Endod J. 2023;18(3):159-164. doi: 10.22037/iej.v18i3.31364.
The purpose of this study was to investigate the effect of incorporating silver nanoparticles (AgNPs) of herbal origin into mineral trioxide aggregate (MTA) on the push-out bond strength (PBS) and compressive strength (CS) in simulated furcal area perforations.
In this study, simulated furcal area perforations (1.3 mm in diameter and 2 mm in depth) were created in 40 extracted human lower molar teeth, which were divided into two groups (=20): MTA alone and MTA combined with AgNPs (2% wt). Using a universal testing machine, PBS was evaluated by performing push-out tests, while CS was assessed using cylindrical specimens. The normal distribution of data was checked using the Kolmogorov-Smirnov test, and statistical analysis was performed using two-way ANOVA.
The CS results showed no significant difference between the MTA group at 4 and 21 days (=0.297), but a significant difference was observed in the nanosilver/MTA group (=0.013). However, there was no significant difference in the push-out bond strength among the study groups (>0.05).
The incorporation of herbal origin silver nanoparticles did not significantly affect the PBS or CS of MTA.
本研究的目的是调查将草药来源的银纳米颗粒(AgNPs)加入三氧化矿物凝聚体(MTA)中对模拟根分叉区穿孔的推出粘结强度(PBS)和抗压强度(CS)的影响。
在本研究中,在40颗拔除的人类下颌磨牙上制作模拟根分叉区穿孔(直径1.3毫米,深度2毫米),将其分为两组(每组 = 20):单独使用MTA组和MTA与AgNPs(2%重量)联合使用组。使用万能试验机,通过进行推出试验评估PBS,同时使用圆柱形试件评估CS。使用Kolmogorov-Smirnov检验检查数据的正态分布,并使用双向方差分析进行统计分析。
CS结果显示,MTA组在4天和21天时无显著差异(P = 0.297),但在纳米银/MTA组观察到显著差异(P = 0.013)。然而,各研究组之间的推出粘结强度无显著差异(P>0.05)。
加入草药来源的银纳米颗粒对MTA的PBS或CS没有显著影响。