Wicks A B, Menter R R
Chest. 1986 Sep;90(3):406-10. doi: 10.1378/chest.90.3.406.
Traumatic spinal cord injuries frequently result in respiratory insufficiency. With intensive medical support, many of these patients live productive lives in spite of severe neurologic deficit. A ten-year review of ventilator-dependent quadriplegic patients at Craig Rehabilitation Hospital was undertaken to determine the number of patients who could be weaned from mechanical ventilation and their long-term survival rate. Ventilator dependency is defined as requiring continuous mechanical ventilatory support for 30 or more days. Of the 134 patients that were included in the study, 76 were weaned during initial hospitalization. Factors which adversely affected ability to wean include: 1) high level of neurologic injury, 2) age greater than 50 years, and 3) other associated injuries. Of the ventilator-dependent patients surveyed after leaving the hospital, survival rate at one year was 90 percent (37 of 41), 56 percent (14 of 25), at three years and 33 percent (7 of 21) at five years. We conclude that vigorous medical support and maximal efforts to wean these patients from mechanical ventilation should be undertaken to: minimize the financial and emotional burden of long term institutional care, reduce ventilator dependency, and improve overall quality of life.
创伤性脊髓损伤常导致呼吸功能不全。尽管有严重的神经功能缺损,但在强化医疗支持下,许多此类患者仍能过上有意义的生活。对克雷格康复医院依赖呼吸机的四肢瘫痪患者进行了为期十年的回顾性研究,以确定能够脱离机械通气的患者数量及其长期生存率。呼吸机依赖定义为需要持续机械通气支持30天或更长时间。在纳入研究的134例患者中,76例在初次住院期间成功脱机。对脱机能力产生不利影响的因素包括:1)神经损伤程度高,2)年龄大于50岁,3)其他合并损伤。在出院后接受调查的依赖呼吸机的患者中,一年生存率为90%(41例中的37例),三年生存率为56%(25例中的14例),五年生存率为33%(21例中的7例)。我们得出结论,应给予积极的医疗支持并尽最大努力使这些患者脱离机械通气,以:尽量减少长期机构护理的经济和情感负担,减少对呼吸机的依赖,并提高整体生活质量。