Centre for Nutrition, Mohn Nutrition Research Laboratory, Department of Clinical Medicine, University of Bergen, 5020, Bergen, Norway.
Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Eur J Nutr. 2023 Oct;62(7):2739-2750. doi: 10.1007/s00394-023-03206-9. Epub 2023 Jul 11.
The single nutrient approach in nutrition research lacks the ability to account for synergistic relationships between dietary components. Current evidence suggests that diet quality, reflecting overall dietary intake, may influence muscle health. In a community-based observational study in Western Norway, we examined dietary patterns in relation to muscle mass and strength at age 67-70.
The current analysis was conducted in men and women of The Hordaland Health Study (HUSK), who participated in both the second (HUSK2) and third study wave (HUSK3). Dietary patterns were extracted by principal component analysis (PCA) on food frequency questionnaire (FFQ) data. Individual dietary pattern scores (DPS) for HUSK2 (age 46-49) and HUSK3 (age 67-70), and overall DPS (oDPS) were calculated. Outcome variables were appendicular skeletal muscle mass (ASMM) and handgrip strength (HGS) measured in HUSK3. The relationships of HUSK3 DPS and oDPS with ASMM and HGS were assessed by multivariate linear regression analysis adjusted for potential confounding factors.
We identified three distinct dietary patterns, labelled 'Western', 'Healthy', and 'Sweets-focused'. A significant positive association was observed between the oDPS for the 'Healthy' dietary pattern and ASMM in both men and women at age 67-70. No significant associations were found between HUSK3 DPS or oDPS for any of the identified dietary patterns and HGS in our population.
Higher oDPS on a dietary pattern predominantly rich in fish, vegetables, nuts and seeds, fruit and berries, and eggs was associated with better ASMM at age 67-70. To establish the influence of diet quality on muscle health, further long-term studies with repeated dietary assessments are warranted.
营养研究中的单一营养素方法缺乏考虑膳食成分之间协同关系的能力。目前的证据表明，反映整体饮食摄入的饮食质量可能会影响肌肉健康。在挪威西部的一项基于社区的观察性研究中，我们研究了 67-70 岁时与肌肉质量和力量相关的饮食模式。
目前的分析是在参加 Hordaland 健康研究（HUSK）第二和第三研究波（HUSK3）的男性和女性中进行的。通过主成分分析（PCA）对食物频率问卷（FFQ）数据提取饮食模式。计算 HUSK2（年龄 46-49 岁）和 HUSK3（年龄 67-70 岁）的个体饮食模式评分（DPS）和总体 DPS（oDPS）。HUSK3 中测量的四肢骨骼肌质量（ASMM）和握力（HGS）为结局变量。通过多元线性回归分析调整潜在混杂因素后，评估 HUSK3 DPS 和 oDPS 与 ASMM 和 HGS 的关系。
我们确定了三种不同的饮食模式，分别标记为“西方”、“健康”和“甜食集中”。在男性和女性中，年龄为 67-70 岁时，“健康”饮食模式的 oDPS 与 ASMM 呈显著正相关。在所研究的人群中，未发现 HUSK3 DPS 或任何确定的饮食模式的 oDPS 与 HGS 之间存在显著关联。
富含鱼类、蔬菜、坚果和种子、水果和浆果以及鸡蛋的饮食模式的 oDPS 越高，与 67-70 岁时的 ASMM 越好。为了确定饮食质量对肌肉健康的影响，需要进行进一步的长期研究，进行重复的饮食评估。
