School of Health Sciences, University of Manchester, Manchester M13 9PL, UK.
Manchester University Foundation NHS Trust, Manchester M13 9WL, UK.
Nutrients. 2022 Apr 7;14(8):1537. doi: 10.3390/nu14081537.
The world's population aged ≥65 is expected to rise from one in eleven in 2019 to one in six by 2050. People aged ≥65 are at a risk of undernutrition, frailty, and sarcopenia. The association between these conditions is investigated in a hospital setting. However, there is little understanding about the overlap and adverse health outcomes of these conditions in community-dwelling people. This systematic review aims to quantify the reported prevalence and incidence of undernutrition, frailty, and sarcopenia among older people aged ≥50 living in community dwellings. Searches were conducted using six databases (AMED, CENTRAL, EMBASE, Web of Science, MEDLINE, and CINAHL), and 37 studies were included. Meta-analyses produced weighted combined estimates of prevalence for each condition (Metaprop, Stata V16/MP). The combined undernutrition prevalence was 17% (95% CI 0.01, 0.46, studies = 5; participants = 4214), frailty was 13% (95% CI 0.11, 0.17 studies = 28; participants = 95,036), and sarcopenia was 14% (95% CI 0.09, 0.20, studies = 9; participants = 7656). Four studies reported incidence rates, of which three included data on frailty. Nearly one in five of those aged ≥50 was considered either undernourished, frail, or sarcopenic, with a higher occurrence in women, which may reflect a longer life expectancy generally observed in females. Few studies measured incidence rates. Further work is required to understand population characteristics with these conditions and the overlap between them. PROSPERO registration No. CRD42019153806.
预计到 2050 年,全球 65 岁及以上人口将从 2019 年的每 11 人增加到每 6 人。65 岁及以上人群存在营养不足、虚弱和肌肉减少症的风险。这些情况在医院环境中进行了关联研究。然而,对于社区居住的人群中这些情况的重叠和不良健康后果,人们的了解甚少。本系统评价旨在量化社区居住的≥50 岁老年人营养不足、虚弱和肌肉减少症的报告患病率和发病率。使用六个数据库(AMED、CENTRAL、EMBASE、Web of Science、MEDLINE 和 CINAHL)进行了检索,并纳入了 37 项研究。使用 MetaProp(Stata V16/MP)对每种情况的加权合并患病率进行了荟萃分析。合并的营养不足患病率为 17%(95%CI 0.01,0.46,研究=5;参与者=4214),虚弱为 13%(95%CI 0.11,0.17,研究=28;参与者=95036),肌肉减少症为 14%(95%CI 0.09,0.20,研究=9;参与者=7656)。四项研究报告了发病率,其中三项包括虚弱的数据。近五分之一的≥50 岁人群被认为存在营养不足、虚弱或肌肉减少症,女性的发生率更高,这可能反映了女性普遍存在的更长的预期寿命。很少有研究测量发病率。需要进一步的工作来了解具有这些情况的人群特征以及它们之间的重叠。PROSPERO 注册号 CRD42019153806。