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在埃塞俄比亚家庭指导协会德西示范诊所接受治疗的女性中,停止使用激素避孕药后的生育力恢复情况及其相关因素:一项横断面研究。

Fertility return after hormonal contraceptive discontinuation and associated factors among women attended Family Guidance Association of Ethiopia Dessie model clinic, Northeast Ethiopia: A cross-sectional study.

机构信息

Department of Public Health, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia.

Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

PLoS One. 2023 Jul 11;18(7):e0287440. doi: 10.1371/journal.pone.0287440. eCollection 2023.

Abstract

BACKGROUND

Women who use hormonal contraception face delayed return of fertility upon discontinuation. There was limited evidence of fertility return after hormonal contraceptive discontinuation in the study area. Hence this study assessed fertility return after hormonal contraceptive discontinuation and associated factors among pregnant women attending Family Guidance Association Ethiopia (FGAE) Dessie model clinic, Northeast Ethiopia, 2019.

METHODS

A cross-sectional study was conducted on 423 samples selected by using systematic random sampling. Data were collected by face-to-face interview using a pretested and structured questionnaire and reviewing client records. Data were entered using Epi Data version 3.1 and analyzed using SPSS version 23. Both bi-variable and multivariable binary logistic regressions were used to identify predictors of delayed fertility return. Adjusted odds ratio (AOR) along with a 95% Confidence Interval (CI) was used to measure the strength and the direction of the association and statistical significance was declared at a P-value less than 0.05.

RESULT

The proportion of fertility return among currently pregnant women after discontinuation of any hormonal contraceptive methods was 88.6% (95% CI; (85.6%-92%)). The proportion of fertility return among Depo-Provera, implant, Intrauterine Contraceptive Device (IUCD), and Oral Contraceptive Pill (OCP) users was 75%, 99.1%, 100%, and 97.8% respectively. Age, (AOR = 5.37, (95% CI; (1.48, 13.6)) and using Depo-Provera (AOR = 4.82, 95% CI; (1.89, 14.2)) had a significant association with delayed fertility return.

CONCLUSIONS

The proportion of fertility return among women after discontinuation of any hormonal contraceptive methods was high. Age and using Depo-Provera had a positive association with delayed fertility return. This study recommends a contraceptive counseling approach that addresses concerns about delay in the return of fertility after hormonal contraceptive discontinuation to avoid confusion among family planning users.

摘要

背景

使用激素避孕的女性在停药后生育能力会延迟恢复。在研究区域,关于激素避孕停药后生育力恢复的证据有限。因此,本研究评估了 2019 年在埃塞俄比亚家庭指导协会(FGAE)德西模式诊所就诊的孕妇在停用激素避孕药后生育力恢复的情况及其相关因素。

方法

采用系统随机抽样方法抽取 423 例样本进行横断面研究。使用经过预测试和结构化问卷进行面对面访谈,并查阅客户记录收集数据。使用 EpiData 版本 3.1 录入数据,使用 SPSS 版本 23 进行分析。采用双变量和多变量二项逻辑回归来确定生育力延迟恢复的预测因素。使用调整后的优势比(AOR)及其 95%置信区间(CI)来衡量关联的强度和方向,P 值小于 0.05 表示具有统计学意义。

结果

目前正在使用任何激素避孕方法的孕妇中,停药后生育力恢复的比例为 88.6%(95%CI;(85.6%-92%))。在使用 Depot-Provera、植入物、宫内节育器(IUCD)和口服避孕药(OCP)的女性中,生育力恢复的比例分别为 75%、99.1%、100%和 97.8%。年龄(AOR=5.37,95%CI:(1.48,13.6))和使用 Depot-Provera(AOR=4.82,95%CI:(1.89,14.2))与生育力延迟恢复呈显著相关。

结论

停用任何激素避孕药后,生育力恢复的比例较高。年龄和使用 Depot-Provera 与生育力延迟恢复呈正相关。本研究建议采用一种避孕咨询方法,解决人们对激素避孕药停药后生育力恢复延迟的担忧,以避免计划生育使用者感到困惑。

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5
Return of fertility after discontinuation of contraception: a systematic review and meta-analysis.
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7
Barriers to modern contraceptive methods uptake among young women in Kenya: a qualitative study.
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8
Fertility after intrauterine device removal: a pilot study.
Eur J Contracept Reprod Health Care. 2015 Jun;20(3):223-30. doi: 10.3109/13625187.2015.1010639. Epub 2015 Mar 9.
9
Reasons for contraceptive nonuse among women having unmet need for contraception in developing countries.
Stud Fam Plann. 2014 Jun;45(2):151-69. doi: 10.1111/j.1728-4465.2014.00382.x.
10
Ethiopia: an emerging family planning success story.
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