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2018-2020 年哥伦比亚两所大学医院的脑静脉血栓形成患者的特征。

Characteristics of cerebral venous thrombosis in patients from two university hospitals in Colombia between 2018-2020.

机构信息

Sección de Neurología, Neuromédica, Medellín, Colombia.

Sección Neurología, Hospital de San José, Fundación Universitaria de Ciencias de la Salud, Bogotá, D.C..

出版信息

Biomedica. 2023 Jun 30;43(2):213-221. doi: 10.7705/biomedica.6877.

Abstract

INTRODUCTION

Cerebral venous thrombosis is an uncommon cause of cerebrovascular disease, which has been increasing worldwide. In Colombia, there are not enough recent studies that allow us to determine epidemiological characteristics of the disease in our population to identify more frequent risk factors and complications according to our living conditions.

OBJETIVE

To describe clinical, demographic, and radiographic characteristics, and risk factors in a cohort of patients with cerebral venous thrombosis attended at two hospitals in Colombia.

MATERIALS AND METHODS

Retrospective descriptive study with patients treated in the hospitalization neurology service of two hospitals in Bogotá, Colombia from December 2018 to December 2020.

RESULTS

Thirty-three patients were included. There was a higher incidence of cerebral venous thrombosis in women of childbearing age in the puerperium (n=7; 33.3%) and associated with autoimmune diseases (n=10; 30.3%). The most common initial symptom was headache (n=31; 93.9 %), followed by neurological focal signs (n=9; 27.2%) and seizures (n=8; 24.2%). Fifty-one percent (n=17) of the patients had a normal physical examination. Cerebral venous infarction occurred in 21.1 % (n=7), subarachnoid hemorrhage in 12.1 % (n=4), and intraparenchymal hematoma in 9 % (n=3) of all the patients. Sixty-point six percent (n=20) of the patients had a total independent Barthel functional scale. None of those died.

CONCLUSIONS

We found similar sociodemographic, clinical, and radiography characteristics to those reported in the world literature. Regarding the differences, deep cerebral venous circulation was higher than that described in previous studies but without complications increase or mortality.

摘要

简介

脑静脉血栓形成是一种少见的脑血管疾病,其在全球范围内呈上升趋势。在哥伦比亚,目前缺乏足够的最新研究来确定我们人群中该病的流行病学特征,以便根据我们的生活条件确定更常见的危险因素和并发症。

目的

描述在哥伦比亚两家医院就诊的一组脑静脉血栓形成患者的临床、人口统计学和影像学特征及危险因素。

材料和方法

这是一项回顾性描述性研究,纳入了 2018 年 12 月至 2020 年 12 月在哥伦比亚波哥大的两家医院住院神经科接受治疗的患者。

结果

共纳入 33 例患者。产后(n=7;33.3%)的育龄期女性和伴有自身免疫性疾病的患者(n=10;30.3%)脑静脉血栓形成发病率更高。最常见的首发症状是头痛(n=31;93.9%),其次是神经系统局灶性体征(n=9;27.2%)和癫痫发作(n=8;24.2%)。51%(n=17)的患者体格检查正常。21.1%(n=7)的患者发生脑静脉梗死,12.1%(n=4)发生蛛网膜下腔出血,9%(n=3)的患者发生脑实质血肿。20 例(60.6%)患者的 Barthel 功能独立量表总分为满分。无患者死亡。

结论

我们发现,患者的社会人口学、临床和影像学特征与世界文献报道的相似。关于差异,深脑静脉循环高于之前研究报道,但无并发症增加或死亡率增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e140/10532268/0ebf8c70c33a/2590-7379-bio-43-02-6877-gf1.jpg

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