Department of Neurosurgery, Zuyderland Medical Centre Heerlen, Heerlen, The Netherlands
Caphri School of Public Health an Primary Care, Maastricht University, Maastricht, The Netherlands.
BMJ Open. 2023 Jul 11;13(7):e073535. doi: 10.1136/bmjopen-2023-073535.
Despite the availability of general and national guidelines for the conduct and reporting of economic evaluations, there is heterogeneity in economic evolutions concerning spine surgery. This is partly the result of differing levels of adherence to the existing guidelines and the lack of disease-specific recommendations for economic evaluations. The extensive heterogeneity in study design, follow-up duration and outcome measurements limit the comparability of economic evaluations in spine surgery. This study has three objectives: (1) to create disease-specific recommendations for the design and conduct of trial-based economic evaluations in spine surgery, (2) to define recommendations for reporting economic evaluations in spine surgery as a complement to the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 2022 checklist and (3) to discuss methodological challenges and defining the need for future research.
A modified Delphi method according to the RAND/UCLA Appropriateness Method.
A four-step process was followed to create and validate disease-specific statements and recommendations for the conduct and reporting of trial-based economic evaluations in spine surgery. Consensus was defined as >75% agreement.
A total of 20 experts were included in the expert group. Validation of the final recommendations was obtained in a Delphi panel, which consisted of 40 researchers in the field who were not included in the expert group.
The primary outcome measure is a set of recommendations for the conduct and reporting, as a complement to the CHEERS 2022 checklist, of economic evaluations in spine surgery.
A total of 31 recommendations are made. The Delphi panel confirmed consensus on all of the recommendations in the proposed guideline.
This study provides an accessible and practical guideline for the conduct of trial-based economic evaluations in spine surgery. This disease-specific guideline is a complement to existing guidelines, and should aid in reaching uniformity and comparability.
尽管有一般和国家指南可用于指导和报告经济评估，但脊柱外科的经济评估仍存在异质性。这部分是由于对现有指南的遵守程度不同，以及缺乏针对经济评估的特定疾病建议。研究设计、随访时间和结果测量的广泛异质性限制了脊柱外科经济评估的可比性。本研究有三个目的：（1）为脊柱外科基于试验的经济评估的设计和实施制定特定疾病的建议，（2）为脊柱外科经济评估报告制定建议，作为对 2022 年 CHEERS 清单的补充，（3）讨论方法学挑战并确定未来研究的需求。
根据 RAND/UCLA 适宜性方法进行的改良 Delphi 方法。
采用四步流程制定和验证脊柱外科基于试验的经济评估的设计和报告的特定疾病声明和建议。共识定义为>75%的一致同意。
共有 20 名专家被纳入专家组。最终建议的验证是在德尔菲小组中获得的，该小组由该领域的 40 名研究人员组成，他们未被纳入专家组。
主要结果测量是一套针对脊柱外科经济评估的实施和报告的建议，作为对 CHEERS 2022 清单的补充。
共提出了 31 条建议。德尔菲小组对拟议指南中的所有建议均达成共识。
本研究为脊柱外科基于试验的经济评估提供了一个易于理解且实用的指南。该特定疾病指南是对现有指南的补充，应有助于实现一致性和可比性。
