Everaerd D S, Biere-Rafi S
Tijdschr Psychiatr. 2023;65(6):347-353.
Persistent symptoms after COVID-19 are a global problem, and it is becoming increasingly clear that they include neuropsychiatric symptoms.
To provide an overview of current knowledge on clinical presentation, risk factors, prevention and treatment of neuropsychiatric symptoms and disorders after COVID-19.
PRISMA literature search.
Anxiety, depression and posttraumatic stress symptoms are common after COVID-19. Cognitive symptoms are also very common and appear to be persistent, while data on risk factors to develop these symptoms is scarce. Women and patients after ICU admission, delirium or with somatic comorbidities have a higher risk of developing post COVID psychiatric symptoms. Vaccination may have a protective effect. Furthermore, there is a lack of evidence on effective treatment strategies for COVID-19-related neurocognitive symptoms.
More research on risk factors, identification and especially effective treatment options for neuropsychiatric symptoms after COVID-19 is needed. In the meantime, guidelines on disorders with a similar clinical presentation could potentially play a role in the diagnosis and treatment of persistent neuropsychiatric symptoms after COVID-19.
新冠病毒病（COVID-19）后的持续症状是一个全球性问题，而且越来越明显的是，这些症状包括神经精神症状。
概述关于COVID-19后神经精神症状和障碍的临床表现、危险因素、预防及治疗的现有知识。
采用PRISMA文献检索法。
焦虑、抑郁和创伤后应激症状在COVID-19后很常见。认知症状也非常普遍且似乎具有持续性，而关于出现这些症状的危险因素的数据却很稀少。女性以及入住重症监护病房（ICU）后、出现谵妄或患有躯体合并症的患者出现COVID后精神症状的风险更高。接种疫苗可能具有保护作用。此外，缺乏关于COVID-19相关神经认知症状有效治疗策略的证据。
需要对COVID-19后神经精神症状的危险因素、识别，尤其是有效治疗方案进行更多研究。与此同时，具有相似临床表现的疾病指南可能在COVID-19后持续性神经精神症状的诊断和治疗中发挥作用。
