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非住院 COVID-19 患者有更频繁的长新冠症状。

Non-hospitalised COVID-19 patients have more frequent long COVID-19 symptoms.

机构信息

Chest Department, Assiut University, Assiut, Egypt.

Department of Public Health and Community Medicine, Assiut University, Assiut, Egypt.

出版信息

Int J Tuberc Lung Dis. 2021 Sep 1;25(9):732-737. doi: 10.5588/ijtld.21.0135.

DOI:10.5588/ijtld.21.0135
PMID:34802495
Abstract

Long COVID-19 syndrome refers to the persistence of symptoms for more than 12 weeks after the start of acute symptoms. The pathophysiology of this syndrome is not yet clear. To assess long COVID-19 symptoms in hospitalised and non-hospitalised patients. A cross-sectional survey was used. The study included 262 patients who were divided into two groups based on their hospital admission history: 167 (63.7%) were not hospitalised, while 95 (36.3%) were hospitalised. Long-COVID was reported in 157 out of 262 patients (59.9%), and was significantly more frequent in non-hospitalised patients (68.3% vs. 45.3%; < 0.001). During the acute phase, hospitalised patients had more respiratory symptoms (95.9% vs. 85.6%), while non-hospitalised patients had more neuropsychiatric symptoms (84.4% vs. 69.5%; < 0.05). Constitutional and neuropsychiatric symptoms were the most frequently reported persistent symptoms in both groups, but all persistent symptoms were more frequent in the non-hospitalised group ( < 0.005). Long COVID-19 symptoms affect both hospitalised and non-hospitalised patients. Neuropsychiatric manifestations were the most common persistent COVID-19 symptoms. Rehabilitation and psychotherapy could be advised for all recovered COVID-19 patients. Non-hospitalised COVID-19 patients should be counselled to contact healthcare providers whenever needed.

摘要

新冠长期症状是指急性症状发作后 12 周以上仍持续存在的症状。其病理生理学机制尚未明确。为评估住院和非住院患者的新冠长期症状,采用横断面调查。研究纳入了 262 例患者,根据住院史分为两组:167 例(63.7%)未住院,95 例(36.3%)住院。262 例患者中有 157 例(59.9%)报告有新冠长期症状,非住院患者明显更为常见(68.3% vs. 45.3%;<0.001)。在急性期,住院患者有更多的呼吸道症状(95.9% vs. 85.6%),而非住院患者有更多的神经精神症状(84.4% vs. 69.5%;<0.05)。两组均以全身症状和神经精神症状为最常见的持续性症状,但非住院患者的所有持续性症状均更为常见(<0.005)。新冠长期症状影响住院和非住院患者。神经精神表现是最常见的持续性新冠症状。建议对所有康复的新冠患者进行康复和心理治疗。应告知非住院新冠患者在有需要时随时联系医疗保健提供者。

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